The Longer-Term Effects of a Single Bupivacaine Exposure on the Mechanical Properties of Native Cartilage Explants.
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DOI: 10.1177/19476035231164751
Abstract: OBJECTIVE The purpose of this study was to determine the in vitro effects of a single exposure of bupivacaine on the mechanical properties of bovine cartilage explants at 3 weeks. DESIGN Femoral condyle articular cartilage… read more here.
Keywords: bupivacaine exposure; bupivacaine; cartilage explants; mechanical properties ... See more keywords
Sprifermin (rhFGF18) modulates extracellular matrix turnover in cartilage explants ex vivo
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DOI: 10.1186/s12967-017-1356-8
Abstract: BackgroundSprifermin (recombinant human fibroblast growth factor 18) is in clinical development as a potential disease-modifying osteoarthritis drug (DMOAD). In vitro studies have shown that cartilage regenerative properties of sprifermin involve chondrocyte proliferation and extracellular matrix… read more here.
Keywords: cartilage explants; ecm turnover; turnover; extracellular matrix ... See more keywords
Cerium oxide nanoparticles protect against chondrocytes and cartilage explants from oxidative stress via Nrf2/HO-1 pathway in temporomandibular joint osteoarthritis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2023.1076240
Abstract: Oxidative stress is closely linked to the etiology of temporomandibular joint osteoarthritis. (TMJ-OA) and is an important therapeutic target. Cerium oxide nanoparticles (CNPs) have been broadly studied owing to their powerful antioxidant properties and potential… read more here.
Keywords: oxidative stress; cartilage; temporomandibular joint; cartilage explants ... See more keywords
Chondroitin Sulfate-Tyramine-Based Hydrogels for Cartilage Tissue Repair
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DOI: 10.3390/ijms24043451
Abstract: The degradation of cartilage, due to trauma, mechanical load or diseases, results in abundant loss of extracellular matrix (ECM) integrity and development of osteoarthritis (OA). Chondroitin sulfate (CS) is a member of the highly sulfated… read more here.
Keywords: mechanical load; cartilage; chondroitin sulfate; cartilage explants ... See more keywords