Neuropeptide Y Acts Directly on Cartilage Homeostasis and Exacerbates Progression of Osteoarthritis Through NPY2R
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DOI: 10.1002/jbmr.3991
Abstract: Neuropeptide Y (NPY) is known to regulate bone homeostasis; however, its functional role as a risk factor during osteoarthritis (OA) remains elusive. In this study, we aim to investigate the direct effect of NPY on… read more here.
Keywords: homeostasis; acts directly; cartilage homeostasis; directly cartilage ... See more keywords
Endogenous adenosine maintains cartilage homeostasis and exogenous adenosine inhibits osteoarthritis progression
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DOI: 10.1038/ncomms15019
Abstract: Osteoarthritis (OA) is characterized by cartilage destruction and chondrocytes have a central role in this process. With age and inflammation chondrocytes have reduced capacity to synthesize and maintain ATP, a molecule important for cartilage homeostasis.… read more here.
Keywords: adenosine maintains; cartilage homeostasis; maintains cartilage; adenosine ... See more keywords
Extracellular vesicles in cartilage homeostasis and osteoarthritis
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DOI: 10.1097/bor.0000000000000454
Abstract: Purpose of review Extracellular vesicles carry bioactive molecules that can be transferred between cells and tissues. The purpose of this review is to describe how extracellular vesicles regulate functions of cells in cartilage and other… read more here.
Keywords: extracellular vesicles; vesicles cartilage; osteoarthritis; cartilage homeostasis ... See more keywords
MicroRNAs and long non-coding RNAs in cartilage homeostasis and osteoarthritis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.1092776
Abstract: During the last decade, osteoarthritis (OA) has become one of the most prevalent musculoskeletal diseases worldwide. OA is characterized by progressive loss of articular cartilage, abnormal remodeling of subchondral bone, hyperplasia of synovial cells, and… read more here.
Keywords: coding rnas; cartilage; micrornas long; cartilage homeostasis ... See more keywords
Brief research report: Effects of Pinch deficiency on cartilage homeostasis in adult mice
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1116128
Abstract: Pinch1 and Pinch2 are LIM domain-containing proteins with crucial functions in mediating focal adhesion formation. Our previous studies have demonstrated that Pinch1/2 expression is essential for cartilage and bone formation during skeletal development in mice.… read more here.
Keywords: adult; cartilage; pinch deficiency; mice ... See more keywords
Cartilage Homeostasis Affects Femoral Head Necrosis Induced by Methylprednisolone in Broilers
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DOI: 10.3390/ijms21144841
Abstract: (1) Background: Since the large-scale poultry industry has been established, femoral head necrosis (FHN) has always been a major leg disease in fast-growing broilers worldwide. Previous research suggested that cartilage homeostasis could be taken into… read more here.
Keywords: homeostasis; head necrosis; femoral head; group ... See more keywords
Regulation of FGF-2, FGF-18 and Transcription Factor Activity by Perlecan in the Maturational Development of Transitional Rudiment and Growth Plate Cartilages and in the Maintenance of Permanent Cartilage Homeostasis
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DOI: 10.3390/ijms23041934
Abstract: The aim of this study was to highlight the roles of perlecan in the regulation of the development of the rudiment developmental cartilages and growth plate cartilages, and also to show how perlecan maintains permanent… read more here.
Keywords: growth; growth plate; cartilage; transcription factor ... See more keywords
Cartilage Homeostasis and Osteoarthritis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23116316
Abstract: Healthy limb joints are important for maintaining health and attaining longevity. Endochondral ossification (the replacement of cartilage with bone, occurring during skeletal development) is essential for bone formation, especially in long-axis bones. In contrast to… read more here.
Keywords: cartilage homeostasis; pathology; cartilage; homeostasis osteoarthritis ... See more keywords