Preparation and Characterization of Electrospun Blend Fibrous Polyethylene Oxide:Polycaprolactone Scaffolds to Promote Cartilage Regeneration
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Engineering Materials"
DOI: 10.1002/adem.202000131
Abstract: Fibrous scaffolds can be used to mimic the structure of cartilage extracellular matrix aiming at cartilage regeneration through optimal utilization of such scaffolds and chondrogenic cells. Herein, different types of fibrous structures are manufactured through… read more here.
Keywords: polycaprolactone; polyethylene oxide; preparation characterization; cartilage ... See more keywords
Harnessing Bifunctional Ferritin with Kartogenin Loading for Mesenchymal Stem Cell Capture and Enhancing Chondrogenesis in Cartilage Regeneration
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202101715
Abstract: Methods that leverage bone marrow mesenchymal stem cells (BMSCs) and stimulating factor kartogenin (KGN) for chondrocyte differentiation have paved the way for cartilage repair. However, the scarce carriers for efficiently bridging the two components significantly… read more here.
Keywords: ferritin; cartilage; chondrogenesis cartilage; mesenchymal stem ... See more keywords
In Vivo Stable Allogenic Cartilage Regeneration in a Goat Model Based on Immunoisolation Strategy Using Electrospun Semipermeable Membranes
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202203084
Abstract: Tissue engineering is a promising strategy for cartilage defect repair. However, autologous cartilage regeneration is limited by additional trauma to the donor site and a long in vitro culture period. Alternatively, allogenic cartilage regeneration has… read more here.
Keywords: cartilage; immunoisolation; strategy; cartilage regeneration ... See more keywords
Development of chondrocyte‐laden alginate hydrogels with modulated microstructure and properties for cartilage regeneration
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology Progress"
DOI: 10.1002/btpr.3322
Abstract: Alginate hydrogel is an attractive biomaterial for cell microencapsulation. The microarchitecture of hydrogels can regulate cellular functions. This study aims to investigate the applicability of sodium citrate buffer (SCB) as a culture medium supplement for… read more here.
Keywords: microstructure; medium; chondrocyte laden; cartilage regeneration ... See more keywords
Cartilage regeneration with dual‐drug‐releasing injectable hydrogel/microparticle system: In vitro and in vivo study
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30006
Abstract: In this study, we developed an injectable in situ forming hydrogel/microparticle system consisting of two drugs, melatonin and methylprednisolone, to investigate the capability of the system for chondrogenesis in vitro and in vivo. The chemical,… read more here.
Keywords: hydrogel microparticle; cartilage regeneration; microparticle;
Macrophages promote cartilage regeneration in a time‐ and phenotype‐dependent manner
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30694
Abstract: Immune regulation of osteochondral defect regeneration has not yet been rigorously characterized. Although macrophages have been demonstrated to regulate the regeneration process in various tissues, their direct contribution to cartilage regeneration remains to be investigated,… read more here.
Keywords: regeneration; promote cartilage; cartilage; cartilage regeneration ... See more keywords
Harnessing Nucleic Acids Nanotechnology for Bone/Cartilage Regeneration.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202301996
Abstract: The effective regeneration of weight-bearing bone defects and critical-sized cartilage defects remains a significant clinical challenge. Traditional treatments such as autologous and allograft bone grafting have not been successful in achieving the desired outcomes, necessitating… read more here.
Keywords: regeneration; nanotechnology; bone cartilage; cartilage regeneration ... See more keywords
Self-Assemble Silk Fibroin Microcapsules for Cartilage Regeneration through Gene Delivery and Immune Regulation.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202302799
Abstract: Effective treatments for cartilage defects are currently lacking. Gene delivery using proper delivery systems has shown great potential in cartilage regeneration. However, the inflammatory microenvironment generated by the defected cartilage severely affects the system's delivery… read more here.
Keywords: self; cartilage regeneration; silk; delivery ... See more keywords
3D composite engineered using supercritical CO2 decellularized porcine cartilage scaffold, chondrocytes, and PRP: Role in articular cartilage regeneration
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.3162
Abstract: At present, no definitive treatment for articular cartilage defects has been perfected. Most of the previous treatments involved multiple drilling and microfracture over defect sites with repair‐related substances, which poses a limited therapeutic effect. End‐stage… read more here.
Keywords: supercritical co2; articular cartilage; cartilage scaffold; cartilage regeneration ... See more keywords
A Protocol to Prepare Decellularized Stem Cell Matrix for Rejuvenation of Cell Expansion and Cartilage Regeneration.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/7651_2017_27
Abstract: Traditional ex vivo expansion of adult stem cells yields an insufficient quantity of less potent cells. Here we describe the fabrication of decellularized matrix deposited by synovium-derived stem cells (SDSCs). This matrix could serve as… read more here.
Keywords: expansion; decellularized stem; stem; cell ... See more keywords
[Current overview of cartilage regeneration procedures].
Sign Up to like & getrecommendations! Published in 2017 at "Der Orthopade"
DOI: 10.1007/s00132-017-3474-7
Abstract: BACKGROUND Cartilage is an avascular, alymphatic and non-innervated tissue with limited intrinsic repair potential. The high prevalence of cartilage defects and their tremendous clinical importance are a challenge for all treating physicians. AIM This article provides… read more here.
Keywords: overview cartilage; current overview; cartilage regeneration; regeneration procedures ... See more keywords