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   Articles with "cartilage repair" as a keyword



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Research Progress on Injectable Microspheres as New Strategies for the Treatment of Osteoarthritis Through Promotion of Cartilage Repair

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recommendations! Published in 2024 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202400585

Abstract: Osteoarthritis (OA) is a degenerative disease caused by a variety of factors with joint pain as the main symptom, including fibrosis, chapping, ulcers, and loss of cartilage. Traditional treatment can only delay the progression of… read more here.

Keywords: cartilage repair; treatment; research; research progress ... See more keywords

β‐Diketone Functionalized Microspheres Chelate Reactive Iron via Metal Coordination for Cartilage Repair

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recommendations! Published in 2025 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202403933

Abstract: Excessive intracellular iron accumulation can induce mitochondrial dysfunction, leading to chondrocyte ferroptosis, a key contributor to cartilage damage in osteoarthritis (OA). Here, micelle‐microfluidic hydrogel microspheres, featuring keto‐enol‐thiol bridged nano‐sized secondary structures that disintegrate within the… read more here.

Keywords: via metal; iron; iron via; cartilage repair ... See more keywords

Biological Reinforced Concrete for Cartilage Repair With 3D Printing

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recommendations! Published in 2025 at "Advanced Science"

DOI: 10.1002/advs.202416734

Abstract: The development of biomimetic cartilage constructs (BCCs) with natural extracellular matrix (ECM) microenvironments and topological cues to accelerate the reconstruction of natural articular cartilage (NAC) after injury is challenging due to its complex structure, low… read more here.

Keywords: reinforced concrete; biological reinforced; concrete cartilage; repair printing ... See more keywords

Research Progress on Advanced Polymer Hydrogels in Articular Cartilage Repair

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recommendations! Published in 2025 at "Macromolecular Chemistry and Physics"

DOI: 10.1002/macp.202500195

Abstract: Articular cartilage is a highly structured connective tissue that covers joint surfaces and acts as a “bearing” between adjacent bones to reduce friction and impact during daily physiological activities. However, due to the absence of… read more here.

Keywords: cartilage repair; articular cartilage; research progress; cartilage ... See more keywords

Injectable freeze‐dried chitosan‐platelet‐rich‐plasma implants improve marrow‐stimulated cartilage repair in a chronic‐defect rabbit model

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recommendations! Published in 2019 at "Journal of Tissue Engineering and Regenerative Medicine"

DOI: 10.1002/term.2814

Abstract: Bone‐marrow stimulation (BMS) improves knee‐joint function but elicits incomplete repair. Liquid chitosan (CS)–glycerol phosphate/blood clots have been shown to improve BMS‐based cartilage repair. Platelet‐rich‐plasma (PRP)—a rich source of growth factors and cytokines—improves recruitment and chondrogenic… read more here.

Keywords: cartilage repair; freeze dried; chronic defect; repair ... See more keywords

Reliability of the MOCART (Magnetic Resonance Observation of Cartilage Repair Tissue) 2.0 knee score for different cartilage repair techniques—a retrospective observational study

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recommendations! Published in 2021 at "European Radiology"

DOI: 10.1007/s00330-021-07688-1

Abstract: To evaluate the reliability of the MOCART 2.0 knee score in the radiological assessment of repair tissue after different cartilage repair procedures. A total of 114 patients (34 females) who underwent cartilage repair of a… read more here.

Keywords: cartilage repair; mocart; reliability; knee score ... See more keywords

Age-dependent differences in response to partial-thickness cartilage defects in a rat model as a measure to evaluate the efficacy of interventions for cartilage repair

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recommendations! Published in 2018 at "Cell and Tissue Research"

DOI: 10.1007/s00441-018-2914-y

Abstract: The objectives of this study are (1) to examine age-dependent longitudinal differences in histological responses after creation of partial-thickness articular cartilage defects (PTCDs) in rats and to use this model (2) to objectively evaluate the… read more here.

Keywords: cartilage repair; week; age dependent; partial thickness ... See more keywords
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Cartilage repair using stem cells & biomaterials: advancement from bench to bedside.

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recommendations! Published in 2020 at "Molecular biology reports"

DOI: 10.1007/s11033-020-05748-1

Abstract: Osteoarthritis (OA) involves gradual destruction of articular cartilagemanifested by pain, stiffness of joints, and impaired movement especially in knees and hips. Non-vascularity of this tissue hinders its self-regenerative capacity and thus, the application of reparative… read more here.

Keywords: repair using; cartilage repair; stem cells; cartilage ... See more keywords
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Key considerations on the development of biodegradable biomaterials for clinical translation of medical devices: With cartilage repair products as an example

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recommendations! Published in 2022 at "Bioactive Materials"

DOI: 10.1016/j.bioactmat.2021.07.031

Abstract: With the interdisciplinary convergence of biology, medicine and materials science, both research and clinical translation of biomaterials are progressing at a rapid pace. However, there is still a huge gap between applied basic research on… read more here.

Keywords: cartilage repair; research; translation; clinical translation ... See more keywords

MSC exosomes mediate cartilage repair by enhancing proliferation, attenuating apoptosis and modulating immune reactivity.

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recommendations! Published in 2018 at "Biomaterials"

DOI: 10.1016/j.biomaterials.2017.11.028

Abstract: Mesenchymal stem cell (MSC) exosome was previously shown to be effective in repairing critical size osteochondral defects in an immunocompetent rat model. Here we investigate the cellular processes modulated by MSC exosomes and the mechanism… read more here.

Keywords: cartilage repair; msc exosomes; proliferation; exosome mediated ... See more keywords

Cell compaction influences the regenerative potential of passaged bovine articular chondrocytes in an ex vivo cartilage defect model.

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recommendations! Published in 2017 at "Journal of bioscience and bioengineering"

DOI: 10.1016/j.jbiosc.2016.11.002

Abstract: The loss and degradation of articular cartilage tissue matrix play central roles in the process of osteoarthritis (OA). New models for evaluating cartilage repair/regeneration are thus of great value for transferring various culture systems into… read more here.

Keywords: cartilage repair; defect model; cell; cartilage ... See more keywords