Modulation of the catalytic performance of OYE3 by engineering key residues at the entrance of the catalytic pocket.
Sign Up to like & getrecommendations! Published in 2023 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2468
Abstract: The amino acid residues at the entrance of the catalytic pocket may impose steric hindrance on the substrate to enter the active center of the enzyme. Based on the analysis of the three-dimensional structure of… read more here.
Keywords: residues entrance; catalytic pocket; carvone; activity ... See more keywords
Synthesis of novel carvone (meth)acrylate monomers for the production of hydrophilic polymers with high terpene content
Sign Up to like & getrecommendations! Published in 2020 at "Polymer International"
DOI: 10.1002/pi.6096
Abstract: The terpene‐based monomers and polymers reported in the literature are mostly hydrophobic and this is limiting their use in aqueous environments. To address this drawback, we have developed a novel synthetic strategy to functionalise a… read more here.
Keywords: novel; terpene; meth acrylate; carvone ... See more keywords
In silico study of carvone derivatives as potential neuraminidase inhibitors
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Modeling"
DOI: 10.1007/s00894-018-3619-6
Abstract: Recent outbreaks of highly pathogenic influenza strains have highlighted the need to develop new anti-influenza drugs. Here, we report an in silico study of carvone derivatives to analyze their binding modes with neuraminidase (NA) active… read more here.
Keywords: silico study; derivatives potential; study carvone; carvone derivatives ... See more keywords
Salicylic acid mediated up regulation of carvone biosynthesis during growth phase in cell suspension cultures of Anethum graveolens
Sign Up to like & getrecommendations! Published in 2020 at "3 Biotech"
DOI: 10.1007/s13205-020-02470-4
Abstract: The study illustrates the system for enhanced production of a medicinally important unexplored compound, carvone occurring naturally in Anethum graveolens. The effect of salicylic acid (SA) on biomass yield, carvone biosynthesis, growth and major enzymatic… read more here.
Keywords: cell; cell suspension; anethum graveolens; carvone ... See more keywords
Fumigant toxicity and physiological effects of spearmint (Mentha spicata, Lamiaceae) essential oil and its major constituents against Reticulitermes dabieshanensis
Sign Up to like & getrecommendations! Published in 2021 at "Industrial Crops and Products"
DOI: 10.1016/j.indcrop.2021.113894
Abstract: Abstract This study evaluated the chemical components of spearmint essential oil, and determined individually the efficacy of spearmint EO and its major constituents, and their mutual binary combination against Reticulitermes dabieshanensis. We also evaluated the… read more here.
Keywords: major constituents; carvone; limonene; essential oil ... See more keywords
C-C Bond Cleavage of α-Pinene Derivatives Prepared from Carvone as a General Strategy for Complex Molecule Synthesis.
Sign Up to like & getrecommendations! Published in 2022 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.1c00783
Abstract: ConspectusThe preparation of complex molecules (e.g., biologically active secondary metabolites) remains an important pursuit in chemical synthesis. By virtue of their sophisticated architectures, complex natural products inspire total synthesis campaigns that can lead to completely… read more here.
Keywords: cleavage; structure; chiral pool; synthesis ... See more keywords
Exploiting Carvone To Demonstrate Both Stereocontrol and Regiocontrol: 1,2- vs 1,4-Addition of Grignard Reagents and Organocuprates
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Chemical Education"
DOI: 10.1021/acs.jchemed.7b00892
Abstract: The ability of certain organometallic reagents to react via 1,2- or 1,4-addition to an α,β-unsaturated ketone is a fundamental example of regioselectivity at the second-year undergraduate organic level. The following two experiments were designed to… read more here.
Keywords: addition; exploiting carvone; demonstrate stereocontrol; stereocontrol regiocontrol ... See more keywords
Carvone-Derived P-Stereogenic Phosphines: Design, Synthesis, and Use in Allene-Imine [3 + 2] Annulation.
Sign Up to like & getrecommendations! Published in 2018 at "ACS catalysis"
DOI: 10.1021/acscatal.8b01081
Abstract: We have prepared a previously unreported family of P-stereogenic [2.2.1] bicyclic chiral phosphines through straightforward syntheses starting from the natural product carvone. This design rationale prompted the development of an unforeseen C-dealkenylation reaction. We have… read more here.
Keywords: derived stereogenic; phosphines design; carvone derived; carvone ... See more keywords
Increased carvone production in Escherichia coli by balancing limonene conversion enzyme expression via targeted quantification concatamer proteome analysis
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-01469-y
Abstract: (−)-Carvone is a monoterpenoid with a spearmint flavor. A sustainable biotechnological production process for (−)-carvone is desirable. Although all enzymes in (−)-carvone biosynthesis have been functionally expressed in Escherichia coli independently, the yield was low… read more here.
Keywords: production; carvone production; proteome analysis; expression ... See more keywords
Rapid construction of the ABD tricyclic skeleton in meliacarpinin B from carvone enabled by an INOC strategy
Sign Up to like & getrecommendations! Published in 2020 at "Organic chemistry frontiers"
DOI: 10.1039/d0qo00576b
Abstract: A highly diastereoselective synthesis of the ABD skeleton of meliacarpinin B is presented. The construction of the key trans-decalin unit features an intramolecular nitrile oxide-alkene cycloaddtion (INOC) reaction on a readily available carvone derivative. This… read more here.
Keywords: construction; skeleton meliacarpinin; skeleton; strategy ... See more keywords
The headspace-GC/MS: Alternative methodology employed in the bioreduction of (4S)-(+)-carvone mediated by human skin fungus
Sign Up to like & getrecommendations! Published in 2020 at "Biocatalysis and Biotransformation"
DOI: 10.1080/10242422.2020.1743692
Abstract: Abstract The development of more efficient and environmentally friendly analytical methods represents a current focus for the fine chemical industry. In particular, microscale methodologies that are free of solvents/reagents. The headspace-GC/MS (HS-GC) methodology was employed… read more here.
Keywords: methodology; fungus; human skin; headspace ... See more keywords