How bacteria control the CRISPR-Cas arsenal.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in microbiology"
DOI: 10.1016/j.mib.2017.11.005
Abstract: CRISPR-Cas systems are adaptive immune systems that protect their hosts from predation by bacteriophages (phages) and parasitism by other mobile genetic elements (MGEs). Given the potent nuclease activity of CRISPR effectors, these enzymes must be… read more here.
Keywords: bacteria control; cas arsenal; crispr cas; control crispr ... See more keywords
Building the Class 2 CRISPR-Cas Arsenal.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular cell"
DOI: 10.1016/j.molcel.2017.01.024
Abstract: Adaptation of CRISPR-Cas9 for genome-editing applications has revolutionized biomedical research. New single-component effector CRISPR systems are emerging from the bioinformatics pipeline. How can we best harness their power? Three new studies will no doubt facilitate… read more here.
Keywords: building class; cas arsenal; crispr; crispr cas ... See more keywords