CRISPR-Cas based molecular diagnostics for foodborne pathogens.
Sign Up to like & getrecommendations! Published in 2022 at "Critical reviews in food science and nutrition"
DOI: 10.1080/10408398.2022.2153792
Abstract: Foodborne pathogenic infection has brought multifaceted issues to human life, leading to an urgent demand for advanced detection technologies. CRISPR/Cas-based biosensors have the potential to address various challenges that exist in conventional assays such as… read more here.
Keywords: foodborne pathogens; molecular diagnostics; diagnostics foodborne; based molecular ... See more keywords
CRISPR-Cas-based detection for food safety problems: Current status, challenges, and opportunities.
Sign Up to like & getrecommendations! Published in 2022 at "Comprehensive reviews in food science and food safety"
DOI: 10.1111/1541-4337.13000
Abstract: Food safety is one of the biggest public issues occurring around the world. Microbiological, chemical, and physical hazards can lead to food safety issues, which may occur at all stages of the supply chain. In… read more here.
Keywords: food safety; food; detection; cas based ... See more keywords
CRISPR/Cas‐based tools for the targeted control of plant viruses
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Plant Pathology"
DOI: 10.1111/mpp.13252
Abstract: Abstract Plant viruses are known to infect most economically important crops and pose a major threat to global food security. Currently, few resistant host phenotypes have been delineated, and while chemicals are used for crop… read more here.
Keywords: crispr cas; cas based; plant viruses; plant ... See more keywords
CRISPR/Cas-based customization of pooled CRISPR libraries
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0199473
Abstract: Pooled CRISPR libraries are widely used in high-throughput screening to study various biological processes. Various pooled CRISPR libraries have been shared for CRISPR screens and useful tools have been developed to construct researcher’s own libraries,… read more here.
Keywords: pooled crispr; conventional pooled; crispr cas; cas based ... See more keywords
Development and Application of CRISPR-Cas Based Tools
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.834646
Abstract: Abundant CRISPR-Cas systems in nature provide us with unlimited valuable resources to develop a variety of versatile tools, which are powerful weapons in biological discovery and disease treatment. Here, we systematically review the development of… read more here.
Keywords: crispr; development; cas based; crispr cas ... See more keywords
Molecular Mechanisms Underlying CRISPR/Cas-Based Assays for Nucleic Acid Detection
Sign Up to like & getrecommendations! Published in 2023 at "Current Issues in Molecular Biology"
DOI: 10.3390/cimb45010043
Abstract: Applied to investigate specific sequences, nucleic acid detection assays can help identify novel bacterial and viral infections. Most up-to-date systems combine isothermal amplification with Cas-mediated detection. They surpass standard PCR methods in detection time and… read more here.
Keywords: nucleic acid; detection; isothermal amplification; cas based ... See more keywords
CRISPR/Cas-Based Approaches to Study Schizophrenia and Other Neurodevelopmental Disorders
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010241
Abstract: The study of diseases of the central nervous system (CNS) at the molecular level is challenging because of the complexity of neural circuits and the huge number of specialized cell types. Moreover, genomic association studies… read more here.
Keywords: schizophrenia neurodevelopmental; study schizophrenia; approaches study; based approaches ... See more keywords
Advances and Challenges in CRISPR/Cas-Based Fungal Genome Engineering for Secondary Metabolite Production: A Review
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Fungi"
DOI: 10.3390/jof9030362
Abstract: Fungi represent an important source of bioactive secondary metabolites (SMs), which have wide applications in many fields, including medicine, agriculture, human health, and many other industries. The genes involved in SM biosynthesis are usually clustered… read more here.
Keywords: genetic engineering; fungal genetic; cas based; cas ... See more keywords