CRISPR/Cas‐mediated Fubp1 silencing disrupts circadian oscillation of Per1 protein via downregulating Syncrip expression
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biology International"
DOI: 10.1002/cbin.11242
Abstract: Most living organisms have physiological and behavioral circadian rhythms controlled by molecular clocks. In mammals, several core clock genes show self‐perpetuating oscillation profiles of their messenger RNAs (mRNAs) and proteins through an auto‐regulatory transcription–translation feedback… read more here.
Keywords: per1 protein; cas mediated; crispr cas; oscillation ... See more keywords
CRISPR/Cas-Mediated In Planta Gene Targeting.
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DOI: 10.1007/978-1-4939-7003-2_1
Abstract: The recent emergence of the CRISPR/Cas system has boosted the possibilities for precise genome engineering approaches throughout all kingdoms of life. The most common application for plants is targeted mutagenesis, whereby a Cas9-mediated DNA double-strand… read more here.
Keywords: gene targeting; cas mediated; crispr cas; planta gene ... See more keywords
Native CRISPR-Cas-Mediated Genome Editing Enables Dissecting and Sensitizing Clinical Multidrug-Resistant P. aeruginosa.
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.10.006
Abstract: Despite being fundamentally important and having direct therapeutic implications, the functional genomics of the clinical isolates of multidrug-resistant (MDR) pathogens is often impeded by the lack of genome-editing tools. Here, we report the establishment of… read more here.
Keywords: native crispr; genome editing; cas mediated; crispr cas ... See more keywords
CRISPR-Cas-mediated chromosome engineering for crop improvement and synthetic biology.
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DOI: 10.1038/s41477-021-00910-4
Abstract: Plant breeding relies on the presence of genetic variation, as well as on the ability to break or stabilize genetic linkages between traits. The development of the genome-editing tool clustered regularly interspaced short palindromic repeats… read more here.
Keywords: plant; cas mediated; crispr cas; cas ... See more keywords
CRISPR/Cas-Mediated Resistance against Viruses in Plants
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DOI: 10.3390/ijms23042303
Abstract: CRISPR/Cas9 provides a robust and widely adaptable system with enormous potential for genome editing directed towards generating useful products. It has been used extensively to generate resistance against viruses infecting plants with more effective and… read more here.
Keywords: mediated resistance; resistance; resistance viruses; cas mediated ... See more keywords