Programmable CRISPR-Cas Repression, Activation, and Computation with Sequence-Independent Targets and Triggers.
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DOI: 10.1021/acssynbio.9b00141
Abstract: The programmability of CRISPR-derived Cas9 as a sequence-specific DNA-targeting protein has made it a powerful tool for genomic manipulation in biological research and translational applications. Cas9 activity can be programmably engineered to respond to nucleic… read more here.
Keywords: computation; crispr cas; cas repression; programmable crispr ... See more keywords