Designing a CRISPR/Cas12a- and Au-Nanobeacon-Based Diagnostic Biosensor Enabling Direct, Rapid, and Sensitive miRNA Detection.
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DOI: 10.1021/acs.analchem.2c00401
Abstract: Direct, rapid, sensitive, and selective detection of nucleic acids in complex biological fluids is crucial for medical early diagnosis. We herein combine the trans-cleavage ability of clustered regularly interspaced short palindromic repeats (CRISPR)/Cas12a with Au-nanobeacon… read more here.
Keywords: mirna; crispr cas12a; direct rapid; cas12a nanobeacon ... See more keywords