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Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22062848
Abstract: Cas3 is a ssDNA-targeting nuclease-helicase essential for class 1 prokaryotic CRISPR immunity systems, which has been utilized for genome editing in human cells. Cas3-DNA crystal structures show that ssDNA follows a pathway from helicase domains…
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Keywords:
cas3 nuclease;
crispr;
temperature;
nuclease ... See more keywords