LAUSR

Cas9 deactivation with photocleavable guide RNAs.

Sign Up to like & get
recommendations!
1 Published in 2021 at "Molecular cell"

DOI: 10.1016/j.molcel.2021.02.007

Abstract: Precise control of CRISPR-Cas9 would improve its safety and applicability. Controlled CRISPR inhibition is a promising approach but is complicated by separate inhibitor delivery, incomplete deactivation, and slow kinetics. To overcome these obstacles, we engineered… read more here.

Keywords: guide rnas; deactivation; cas9 deactivation; photocleavable guide ... See more keywords