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Cas9 endonuclease and off-target activity

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0 Published in 2017 at "Science"

DOI: 10.1126/science.357.6350.467-q

Abstract: Genome Sequencing The RNA-guided endonuclease Cas9 has brought about a revolution in genetic engineering and genome editing. However, issues with the system include the off-target activity of the endonuclease and promiscuous cleavage, making accuracy in… read more here.

Keywords: cas9 endonuclease; endonuclease; target activity; endonuclease target ... See more keywords