Articles with "cas9 enzymes" as a keyword



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Orthologous CRISPR-Cas9 enzymes for Combinatorial Genetic Screens

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Published in 2018 at "Nature biotechnology"

DOI: 10.1038/nbt.4048

Abstract: Combinatorial genetic screening using CRISPR–Cas9 is a useful approach to uncover redundant genes and to explore complex gene networks. However, current methods suffer from interference between the single-guide RNAs (sgRNAs) and from limited gene targeting… read more here.

Keywords: crispr cas9; orthologous crispr; combinatorial genetic; cas9 enzymes ... See more keywords