Sequencing data from Massachusetts General Hospital shows Cas9 integration into the genome, highlighting a serious hazard in gene-editing therapeutics
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DOI: 10.12688/f1000research.20744.1
Abstract: The ability to edit a specific gene within our genomes using guided-nucleases (Cas9/ZFN/TALEN - CaZiTa) presents huge opportunities for curing many genetic disorders. Delivery of this ‘drug’ within cells is a critical step for such… read more here.
Keywords: massachusetts general; integration; cas9 integration; general hospital ... See more keywords