Cytosolic microRNA-inducible nuclear translocation of Cas9 protein for disease-specific genome modification
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac431
Abstract: Abstract MicroRNA-dependent mRNA decay plays an important role in gene silencing by facilitating posttranscriptional and translational repression. Inspired by this intrinsic nature of microRNA-mediated mRNA cleavage, here, we describe a microRNA-targeting mRNA as a switch… read more here.
Keywords: translocation; genome modification; cas9 protein;