Articles with "casc15" as a keyword



The lncRNA CASC15 regulates SOX4 expression in RUNX1-rearranged acute leukemia

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Published in 2017 at "Molecular Cancer"

DOI: 10.1186/s12943-017-0692-x

Abstract: BackgroundLong non-coding RNAs (lncRNAs) play a variety of cellular roles, including regulation of transcription and translation, leading to alterations in gene expression. Some lncRNAs modulate the expression of chromosomally adjacent genes. Here, we assess the… read more here.

Keywords: casc15 regulates; lncrna casc15; runx1; expression ... See more keywords
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LncRNA-CASC15 knockdown inhibits the progression of esophageal squamous cell carcinoma through targeting miR-33a-5p/PTGS2 axis.

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Published in 2022 at "Histology and histopathology"

DOI: 10.14670/hh-18-517

Abstract: LncRNA CASC15 has been determined as a novel tumor-related lncRNA in many cancers. However, the in-detail role of CASC15 remains elusive in esophageal squamous cell carcinoma (ESCC). CASC15 expression level was detected in 113 ESCC… read more here.

Keywords: casc15; casc15 knockdown; cell; mir 33a ... See more keywords
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Long non-coding RNA CASC15 is upregulated in hepatocellular carcinoma and facilitates hepatocarcinogenesis

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Published in 2017 at "International Journal of Oncology"

DOI: 10.3892/ijo.2017.4175

Abstract: Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer, accounting for one-sixth of all malignant tumors, and the mortality rate of HCC ranks second among all cancer-related deaths. Increasing evidence has recently… read more here.

Keywords: hepatocellular carcinoma; hcc; long non; non coding ... See more keywords
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lncRNA-CASC15 promotes osteosarcoma proliferation and metastasis by regulating epithelial-mesenchymal transition via the Wnt/β-catenin signaling pathway

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Published in 2021 at "Oncology Reports"

DOI: 10.3892/or.2021.8027

Abstract: Osteosarcoma (OS) is a rare type of tumor and mostly occurs in children and adolescents. Approximately 10–25% of patients with OS have lung metastases, and lung damage caused by lung metastasis is the main cause… read more here.

Keywords: proliferation; metastasis; casc15; cell ... See more keywords

LncRNA CASC15, MiR-23b Cluster and SMAD3 form a Novel Positive Feedback Loop to promote Epithelial-Mesenchymal Transition and Metastasis in Ovarian Cancer

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Published in 2022 at "International Journal of Biological Sciences"

DOI: 10.7150/ijbs.67486

Abstract: Cancer Susceptibility Candidate 15 (CASC15), which is a newly identified long noncoding RNA crucial for epigenetic regulation in human tumors, was found to be associated with poor prognosis of the patients with ovarian cancer by… read more here.

Keywords: cancer; mesenchymal transition; mir 23b; casc15 ... See more keywords