Polypyrrole-iron phosphate-glucose oxidase-based nanocomposite with cascade catalytic capacity for tumor synergistic apoptosis-ferroptosis therapy
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DOI: 10.1016/j.cej.2021.131671
Abstract: Abstract Utilizing the synergistic effect of apoptosis and ferroptosis for tumor elimination is a promising and effective strategy. Herein, a novel PPy-FePO-GOx-PVA nanocomposite with cascade catalytic capacity was designed and fabricated for tumor synergistic apoptosis-ferroptosis… read more here.
Keywords: apoptosis ferroptosis; cascade catalytic; apoptosis; tumor ... See more keywords
Antibacterial Cascade Catalytic Glutathione-Depleting MOF Nanoreactors.
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DOI: 10.1021/acsami.1c24231
Abstract: Nanozymes with peroxidase-like activity have great application potential in combating pathogenic bacterial infections and are expected to become an alternative to antibiotics. However, the near-neutral pH and high glutathione (GSH) levels in the bacterial infection… read more here.
Keywords: catalytic glutathione; cascade catalytic; glutathione depleting; glutathione ... See more keywords
Biomimetic Nanoarchitectonics of Hollow Mesoporous Copper Oxide-Based Nanozymes with Cascade Catalytic Reaction for Near Infrared-II Reinforced Photothermal-Catalytic Therapy.
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DOI: 10.1021/acsami.2c11634
Abstract: Biomimetic nanozyme with natural enzyme-like activities has drawn extensive attention in cancer therapy, while its application was hindered by the limited catalytic efficacy in the complicated tumor microenvironment (TME). Herein, a hybrid biomimetic nanozyme combines… read more here.
Keywords: catalytic efficacy; reaction; cascade catalytic; therapy ... See more keywords
High-fidelity ATP imaging via an isothermal cascade catalytic amplifier
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DOI: 10.1039/d2sc04560e
Abstract: Artificial catalytic DNA circuits that can identify, transduce and amplify the biomolecule of interest have supplemented a powerful toolkit for visualizing various biomolecules in cancer cells. However, the non-specific response in normal tissues and the… read more here.
Keywords: cascade; catalytic amplifier; cascade catalytic; cancer cells ... See more keywords
Highly sensitive detection and intracellular imaging of MicroRNAs based on target-triggered cascade catalytic hairpin assembly.
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DOI: 10.2139/ssrn.4145649
Abstract: MicroRNAs (miRNAs) have been identified as important biomarkers with great significance for diagnosis and treatment of various diseases. However, their unique properties, such as small size, high sequence homology, and low abundance, make quantitative analysis… read more here.
Keywords: hairpin assembly; intracellular imaging; cascade catalytic; catalytic hairpin ... See more keywords