Near‐Infrared‐II Plasmonic Multi‐Enzyme Nanocapsules for Hyperthermia‐Augmented Cascade Catalytic Oncotherapy
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202511582
Abstract: Catalytic therapy based on artificial nanozymes holds considerable potential for cancer treatment but faces clinical challenges due to insufficient catalytic activity, limited enzymatic diversity, and the adaptive antioxidant tumor microenvironment. Herein, a near‐infrared II (NIR‐II)… read more here.
Keywords: plasmonic multi; therapy; multi enzyme; enzyme ... See more keywords
MXene-Based Nanosheets Reverse Tumor Hypoxia to Amplify Triple-Mode Cancer Therapy.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202504533
Abstract: Despite MXene's good biocompatibility and photothermal properties, its poor stability in physiological environments and non-specific characteristics still pose potential risks and limit its application in the anti-tumor field. Herein, an efficient cascade catalytic system is… read more here.
Keywords: cancer; catalytic system; therapy; mxene ... See more keywords
Neutrophil-Mimicking Nanozyme with Cascade Catalytic Releasing Nitric Oxide and Signet Oxygen Property for Synergistic Bimodal Therapy of Methicillin-Resistant Staphylococcus Aureus Infections.
Sign Up to like & getrecommendations! Published in 2024 at "Small"
DOI: 10.1002/smll.202403527
Abstract: Recently, chloroperoxidase (CPO)-mediated enzyme dynamic therapy (EDT) by mimicking the antipathogen function of neutrophils via generating highly active signet oxygen (1O2) has attracted great interest in biomedical applications. However, the therapeutic efficiency of EDT is… read more here.
Keywords: therapy; neutrophil mimicking; mimicking nanozyme; methicillin resistant ... See more keywords
Polypyrrole-iron phosphate-glucose oxidase-based nanocomposite with cascade catalytic capacity for tumor synergistic apoptosis-ferroptosis therapy
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2021.131671
Abstract: Abstract Utilizing the synergistic effect of apoptosis and ferroptosis for tumor elimination is a promising and effective strategy. Herein, a novel PPy-FePO-GOx-PVA nanocomposite with cascade catalytic capacity was designed and fabricated for tumor synergistic apoptosis-ferroptosis… read more here.
Keywords: apoptosis ferroptosis; cascade catalytic; apoptosis; tumor ... See more keywords
Antibacterial Cascade Catalytic Glutathione-Depleting MOF Nanoreactors.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c24231
Abstract: Nanozymes with peroxidase-like activity have great application potential in combating pathogenic bacterial infections and are expected to become an alternative to antibiotics. However, the near-neutral pH and high glutathione (GSH) levels in the bacterial infection… read more here.
Keywords: catalytic glutathione; cascade catalytic; glutathione depleting; glutathione ... See more keywords
Biomimetic Nanoarchitectonics of Hollow Mesoporous Copper Oxide-Based Nanozymes with Cascade Catalytic Reaction for Near Infrared-II Reinforced Photothermal-Catalytic Therapy.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c11634
Abstract: Biomimetic nanozyme with natural enzyme-like activities has drawn extensive attention in cancer therapy, while its application was hindered by the limited catalytic efficacy in the complicated tumor microenvironment (TME). Herein, a hybrid biomimetic nanozyme combines… read more here.
Keywords: catalytic efficacy; reaction; cascade catalytic; therapy ... See more keywords
Bioinspired Cascade-Catalytic Scaffold to Prevent Adverse Remodeling of Heart Valve under Pathological Conditions via Conversion of •O2- into NO.
Sign Up to like & getrecommendations! Published in 2025 at "ACS nano"
DOI: 10.1021/acsnano.5c12816
Abstract: In situ tissue-engineered heart valves (TEHVs) face significant challenges in patients with compromised endogenous repair capacity, particularly those with diabetic comorbidities. To address this issue, we developed a bimetallic nanozyme-functionalized scaffold capable of restoring •O2-/NO… read more here.
Keywords: pathological conditions; heart valve; heart; bioinspired cascade ... See more keywords
High-fidelity ATP imaging via an isothermal cascade catalytic amplifier
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc04560e
Abstract: Artificial catalytic DNA circuits that can identify, transduce and amplify the biomolecule of interest have supplemented a powerful toolkit for visualizing various biomolecules in cancer cells. However, the non-specific response in normal tissues and the… read more here.
Keywords: cascade; catalytic amplifier; cascade catalytic; cancer cells ... See more keywords
Highly sensitive detection and intracellular imaging of MicroRNAs based on target-triggered cascade catalytic hairpin assembly.
Sign Up to like & getrecommendations! Published in 2022 at "Talanta"
DOI: 10.2139/ssrn.4145649
Abstract: MicroRNAs (miRNAs) have been identified as important biomarkers with great significance for diagnosis and treatment of various diseases. However, their unique properties, such as small size, high sequence homology, and low abundance, make quantitative analysis… read more here.
Keywords: hairpin assembly; intracellular imaging; cascade catalytic; catalytic hairpin ... See more keywords