Abstract LB-068: Development of a screening cascade to identify selective small molecule inhibitors of DNMT1
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-lb-068
Abstract: DNA Methyltransferases (or DNMTs) play an important role in genomic integrity. The DNMT family of enzymes catalyse the transfer of methyl groups to specific CpG structures on DNA, with DNMT1 acting as a maintenance methyltransferase… read more here.
Keywords: selective small; development screening; small molecule; cascade ... See more keywords