Inorganic and Metal-Organic Nanocomposites for Cascade-Responsive Imaging and Photochemical Synergistic Effects.
Sign Up to like & getrecommendations! Published in 2020 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.9b03719
Abstract: Porphyrins coordinated with platinum(II) chemotherapeutic drugs are attractive for the development of photosensitizers for photodynamic therapy (PDT) of cancer. In this paper, inorganic and metal-organic nanocomposites were synthesized with cascade-responsive imaging and photochemical synergistic effects.… read more here.
Keywords: cascade responsive; metal organic; organic nanocomposites; metal ... See more keywords
Cascade-Responsive 2-DG Nanocapsules Encapsulate aV-siCPT1C Conjugates to Inhibit Glioblastoma through Multiple Inhibition of Energy Metabolism.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c19285
Abstract: Aerobic glycolysis is the primary energy supply mode for glioblastoma (GBM) cells to maintain growth and proliferation. However, due to the metabolic reprogramming of tumor cells, GBM can still produce energy through fatty acid oxidation… read more here.
Keywords: energy metabolism; energy; nanocapsule; cascade responsive ... See more keywords
Tandem Chemoimmunotherapy by a Cascade-Responsive Molecular Prodrug.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical biology"
DOI: 10.1021/acschembio.1c00933
Abstract: The limited therapeutic effects of immunotherapy for most types of cancer stimulates the pursuit for efficient methods to improve its response rate. Herein we report the design and synthesis of a cascade-responsive molecular prodrug for… read more here.
Keywords: molecular prodrug; chemoimmunotherapy; prodrug; cascade responsive ... See more keywords