Pd/C Catalyzed Cascade Synthesis of 2‐Arylquinazolinones from 2‐Iodoacetanilides Employing Ammonia and CO Precursors
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DOI: 10.1002/cctc.202100152
Abstract: An efficient and straightforward approach has been demonstrated for 2‐aryl quinazolinones synthesis from 2‐iodoacetanilides using ammonium carbamate/ammonium carbonate and oxalic acid under heterogeneous Pd/C catalyzed conditions. Herein, we have carried out the reactions employing oxalic… read more here.
Keywords: synthesis arylquinazolinones; arylquinazolinones iodoacetanilides; cascade synthesis; ammonium ... See more keywords
Aqueous bile salt accelerated cascade synthesis of 1,2,3-triazoles from arylboronic acids
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DOI: 10.1016/j.tetlet.2018.09.064
Abstract: Abstract A facile, efficient and mild copper catalyzed strategy for cascade synthesis of various 1,4-disubstituted 1,2,3-triazoles from arylboronic acids, sodium azide and alkynes was developed by using aqueous bile salt NaDC solution as an accelerating… read more here.
Keywords: triazoles arylboronic; bile salt; aqueous bile; cascade synthesis ... See more keywords
Reusable Supported Pyridine-Mediated Cascade Synthesis of trans-2,3-Dihydroindoles via In Situ-Generated N-Ylide.
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DOI: 10.1021/acs.orglett.3c01295
Abstract: Merrifield resin-anchored pyridines were prepared and applied as reusable mediators for trans-selective cascade synthesis of 2,3-dihydroindoles. The developed approach relied on in situ N-ylide formation followed by Michael substitution reactions. The cascade reaction was also… read more here.
Keywords: reusable supported; cascade synthesis; pyridine mediated; pyridine ... See more keywords
Asymmetric Organocatalytic Cascade Synthesis of Tetrahydrofuranyl Spirooxindoles
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DOI: 10.1055/s-0036-1590918
Abstract: An enantio- and regioselective organocatalytic cascade starting from isatin has been disclosed to construct tetrahydrofuranyl spirooxindoles in high yields and stereoselectivities. Also, a triple cascade leading to the pentacyclic compound with two quaternary and a… read more here.
Keywords: cascade; organocatalytic cascade; cascade synthesis; synthesis tetrahydro ... See more keywords