Cascade-targeting Poly(amino acid) Nanoparticles Eliminate Intracellular Bacteria via on-site Antibiotic Delivery.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced materials"
DOI: 10.1002/adma.202109789
Abstract: Intracellular bacteria in latent or dormant states tolerate high-dose antibiotics. Fighting against these opportunistic bacteria has been a long-standing challenge. Herein, we design a cascade-targeting drug delivery system (DDS) that can sequentially target macrophages and… read more here.
Keywords: cascade targeting; fam nps; intracellular bacteria; rif fam ... See more keywords
A GLUTs/GSH cascade targeting-responsive bioprobe for the detection of circulating tumor cells.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc00566b
Abstract: A GLUTs/GSH cascade targeting-responsive bioprobe, GluCC, was rationally designed and synthesized for the first time via the coordination of copper ions with a glucose-modified coumarin derivative ligand (GluC). GluCC can specifically detect circulating tumor cells… read more here.
Keywords: tumor; gsh cascade; cascade targeting; detection ... See more keywords