Contrasting Case-Control and Normative Reference Approaches to Capture Clinically Relevant Structural Brain Abnormalities in Patients With First-Episode Psychosis Who Are Antipsychotic Naive.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2022.3010
Abstract: Importance To make progress toward precision psychiatry, it is crucial to move beyond case-control studies and instead capture individual variations and interpret them in the context of a normal range of biological systems. Objective To… read more here.
Keywords: brain; patients first; pathology; case ... See more keywords
COVID‐19 vaccines and risks of hematological abnormalities: Nested case–control and self‐controlled case series study
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26478
Abstract: Several studies reported hematological abnormalities after vaccination against the coronavirus disease 2019 (COVID‐19). We evaluated the association between COVID‐19 vaccines (CoronaVac and BNT162b2) and hematological abnormalities. We conducted nested case–control and self‐controlled case series analyses… read more here.
Keywords: vaccination; covid vaccines; case; nested case ... See more keywords
Associations of endocrine stress‐related gene polymorphisms with risk of autism spectrum disorders: Evidence from an integrated meta‐analysis
Sign Up to like & getrecommendations! Published in 2017 at "Autism Research"
DOI: 10.1002/aur.1822
Abstract: Autism spectrum disorders (ASD) are related to serotonin transporter (5‐HTT) and catechol‐O‐methyl transferase (COMT) as two most monoaminergic polymorphic variations. However, multiple studies assessing rs4680 and 5‐HTTLPR variants in ASD have reported inconsistent results. Therefore,… read more here.
Keywords: rs4680; autism; case control; meta analysis ... See more keywords
Association of urinary polycyclic aromatic hydrocarbon metabolites with symptoms among autistic children: A case–control study in Tianjin, China
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DOI: 10.1002/aur.2788
Abstract: Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous pollutants that are associated with altered neurodevelopment and various neurodevelopmental disorders. However, studies evaluating internal biomarkers of PAH exposure in reference to the severity of autism spectrum disorder (ASD)… read more here.
Keywords: autism; case control; polycyclic aromatic; control study ... See more keywords
Association between maternal pregestational diabetes mellitus and spina bifida: A population-based case-control study, Finland, 2000-2014.
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DOI: 10.1002/bdr2.1624
Abstract: BACKGROUND Maternal pregestational diabetes mellitus (PGDM) is a known risk factor for neural tube defects. We examined the association between maternal PGDM and spina bifida in the offspring using PGDM status from medical records in… read more here.
Keywords: bifida; pgdm; association; case control ... See more keywords
Maternal risk factors for the VACTERL association: A EUROCAT case–control study
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DOI: 10.1002/bdr2.1686
Abstract: Abstract Background The VACTERL association (VACTERL) is the nonrandom occurrence of at least three of these congenital anomalies: vertebral, anal, cardiac, tracheoesophageal, renal, and limb anomalies. Despite suggestions for involvement of several genes and nongenetic… read more here.
Keywords: risk; vacterl; risk factors; factors vacterl ... See more keywords
Interaction between Maternal and Paternal SHMT1 C1420T Predisposes to Neural Tube Defects in the Fetus: Evidence from Case-Control and Family-Based Triad Approaches.
Sign Up to like & getrecommendations! Published in 2017 at "Birth defects research"
DOI: 10.1002/bdra.23623
Abstract: BACKGROUND Neural tube defects (NTDs) are caused by the failure of neural tube formation which occurs during early embryonic development. NTDs are the most severe and leading cause of fetal mortality. Serine hydroxymethyl transferase (SHMT1)… read more here.
Keywords: shmt1; case; neural tube; family based ... See more keywords
A case–control study to evaluate the impact of the breast screening programme on breast cancer incidence in England
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DOI: 10.1002/cam4.5004
Abstract: There is uncertainty about overdiagnosis in mammography screening. read more here.
Keywords: evaluate impact; control study; study evaluate; breast ... See more keywords
Implant stability of narrow diameter implants in hyperglycemic patients—A 3‐month case–control study
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DOI: 10.1002/cre2.587
Abstract: The aim of this prospective case–control study was to compare the development of implant stability quotients of narrow diameter implants in patients with type 2 diabetes mellitus (T2DM) and healthy individuals within the first 3… read more here.
Keywords: narrow diameter; control study; implant stability; diameter implants ... See more keywords
A novel association test for multiple secondary phenotypes from a case‐control GWAS
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DOI: 10.1002/gepi.22045
Abstract: In the past decade, many genome‐wide association studies (GWASs) have been conducted to explore association of single nucleotide polymorphisms (SNPs) with complex diseases using a case‐control design. These GWASs not only collect information on the… read more here.
Keywords: association; case control; secondary phenotypes; pom ... See more keywords
The impact on estimations of genetic correlations by the use of super‐normal, unscreened, and family‐history screened controls in genome wide case–control studies
Sign Up to like & getrecommendations! Published in 2020 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22281
Abstract: Traditionally, in normal case–control studies of disorder A, the controls are defined as those not developing the disorder. However, in genome wide association (GWA) studies, controls are sometimes (a) unscreened or (b) screened for both… read more here.
Keywords: genome wide; control studies; genetic correlations; normal controls ... See more keywords