A CASE OF SEVERE ATRIAL MITRAL REGURGITATION IN A NON-SURGICAL PATIENT
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(18)32831-6
Abstract: Secondary mitral regurgitation (MR) is mostly attributed to left ventricular (LV) remodeling and enlargement. The atrial chamber on the other side of the annulus can, however, play a similar role in causing MR. A 68-year-old… read more here.
Keywords: regurgitation; atrial mitral; mitral regurgitation; regurgitation non ... See more keywords
A case of severe Aicardi–Goutières syndrome with a homozygous RNASEH2B intronic variant
Sign Up to like & getrecommendations! Published in 2024 at "Human Genome Variation"
DOI: 10.1038/s41439-024-00291-y
Abstract: We report a case of severe Aicardi–Goutières syndrome caused by a novel homozygous RNASEH2B intronic variant, NC_000013.10(NM_024570.4):c.65-13G > A p.Glu22Valfs*5. The patient was born with pseudo-TORCH symptoms, including intracranial calcification, cataracts, and hepatosplenomegaly. Furthermore, the patient exhibited… read more here.
Keywords: homozygous rnaseh2b; gouti res; aicardi gouti; res syndrome ... See more keywords
A baffling case of severe systemic inflammation. Putting the pieces together: genes, environment and triggers.
Sign Up to like & getrecommendations! Published in 2017 at "Rheumatology"
DOI: 10.1093/rheumatology/kew505
Abstract: Herein we report a complex case with heterozygosity for MEFV with atypical Adult Onset Still’s Disease (AOSD) in a 39-year-old Colombian woman, in her 3rd pregnancy trimester. At 33 weeks gestation, she presented with a… read more here.
Keywords: severe systemic; case; baffling case; inflammation putting ... See more keywords
A case of severe Pembrolizumab-induced neutropenia.
Sign Up to like & getrecommendations! Published in 2018 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000000661
Abstract: Immune checkpoint inhibitors have revolutionized cancer therapy. Given their mechanism of action, immune-related adverse events have been associated with their use. We present the first documented case of pembrolizumab-induced grade IV neutropenia. A 73-year-old women… read more here.
Keywords: case; grade neutropenia; pembrolizumab induced; pembrolizumab ... See more keywords
Massive intestinal liquid retention in a case of severe heat stroke
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Paediatrics and Child Health"
DOI: 10.1111/jpc.14343
Abstract: 1 Elliot C, Marais B, Williams P et al. Tuberculin skin test versus interferon-gamma release assay in refugee children: A retrospective cohort study. J. Paediatr. Child Health 2018; 54: 834–9. 2 Farhat M, Greenaway C,… read more here.
Keywords: intestinal liquid; massive intestinal; retention case; liquid retention ... See more keywords
The first case of severe acute hemolytic transfusion reaction caused by anti‐Sc2
Sign Up to like & getrecommendations! Published in 2018 at "Transfusion"
DOI: 10.1111/trf.14867
Abstract: Alloantibodies to the low‐frequency antigen Scianna‐2 (Sc2) have been implicated in cases of hemolytic disease of the fetus and newborn but never in hemolytic transfusion reactions (HTRs); thus, the clinical significance of anti‐Sc2 has yet… read more here.
Keywords: anti sc2; sc2; hemolytic transfusion; first case ... See more keywords
Elexacaftor, tezacaftor and ivacaftor: a case of severe rash and approach to desensitisation
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2021-247042
Abstract: We present a case of severe rash following induction of elexacaftor, tezacaftor and ivacaftor (ELX/TEZ/IVA) in a young adult male cystic fibrosis patient. While rash is a commonly reported side effect which resolves in 1–2… read more here.
Keywords: severe rash; rash; case severe; elx tez ... See more keywords
Strategic Utilization of Dantrolene in a Case of Severe Acute Generalized Tetanus.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of pharmacy practice"
DOI: 10.1177/08971900231178429
Abstract: Tetanus is a life-threatening, vaccine-preventable disease caused by an endotoxin produced by Clostridium tetani. We report a case of severe tetanus in an adult male with a history of intravenous drug use. The patient presented… read more here.
Keywords: acute; case severe; tetanus; strategic utilization ... See more keywords
An Unusual Case of Severe Persistent Neonatal Thrombocytopenia in an Extremely Low Birth Weight, Extreme Preterm Neonate
Sign Up to like & getrecommendations! Published in 2021 at "Global Pediatric Health"
DOI: 10.1177/2333794x211038724
Abstract: Neonatal thrombocytopenia is a common hematological problem but refractory thrombocytopenia is very rare in neonates. A systematic and diligent workup will result in arriving at the proper diagnosis and providing accurate management in rare causes… read more here.
Keywords: thrombocytopenia extremely; thrombocytopenia; neonatal thrombocytopenia; low birth ... See more keywords
A case of severe Plasmodium ovale malaria with acute respiratory distress syndrome and splenic infarction in a male traveller presenting in Italy
Sign Up to like & getrecommendations! Published in 2024 at "Malaria Journal"
DOI: 10.1186/s12936-024-04911-4
Abstract: Background Plasmodium ovale malaria is usually considered a tropical infectious disease associated with low morbidity and mortality. However, severe disease and death have previously been reported. Case presentation A case of severe P. ovale malaria… read more here.
Keywords: case severe; ovale malaria; plasmodium ovale; splenic infarction ... See more keywords
[A case of severe hypernatremia in a cachectic patient hospitalized for pneumococcal pneumonia].
Sign Up to like & getrecommendations! Published in 2025 at "Annales de biologie clinique"
DOI: 10.1684/abc.2025.1980
Abstract: A 65-year-old man with a history of sequelae from strokes and aspiration pneumonia was hospitalized for a new episode of pneumococcal pneumonia. In the emergency department, laboratory tests revealed severe hypernatremia associated with multiple other… read more here.
Keywords: severe hypernatremia; hypernatremia cachectic; pneumococcal pneumonia; case severe ... See more keywords