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   Articles with "casp" as a keyword



Antidepressant Effect of Paeoniflorin Is Through Inhibiting Pyroptosis CASP-11/GSDMD Pathway

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recommendations! Published in 2020 at "Molecular Neurobiology"

DOI: 10.1007/s12035-020-02144-5

Abstract: Nod-like receptor protein 3 (NLRP3)-associated neuroinflammation mediated by activated microglia is involved in the pathogenesis of depression. The role of the pore-forming protein gasdermin D (GSDMD), a newly identified pyroptosis executioner downstream of NLRP3 inflammasome… read more here.

Keywords: depression; casp; paeoniflorin; pyroptosis ... See more keywords

Behavioral, molecular and physiological responses of embryo-larval zebrafish exposed to types I and II pyrethroids.

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recommendations! Published in 2019 at "Chemosphere"

DOI: 10.1016/j.chemosphere.2018.12.026

Abstract: Pyrethroids are potent neurotoxicants that may elicit multiple pathways of toxicity in non-target organisms. Comparative studies on the mechanistic and developmental effects of types I and II pyrethroids against non-target aquatic species are limited. This… read more here.

Keywords: embryo larval; casp; types pyrethroids; non target ... See more keywords

Single-Cell Caspase-3 Measurement Using a Biomimetic Nanochannel.

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recommendations! Published in 2024 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.3c04782

Abstract: Direct single-cell caspase-3 (Casp-3) analysis has remained challenging. A study of single-cell Casp-3 could contribute to revealing the fundamental pathogenic mechanisms in Casp-3-associated diseases. Here, a biomimetic nanochannel capable of single-cell sampling and ionic detection… read more here.

Keywords: cell caspase; biomimetic nanochannel; single cell; cell ... See more keywords

Activator Strand Modifications in CRISPR/Cas12a: Unlocking the Potential for Casp-3-Targeted Biosensing and Imaging Analysis of Apoptosis.

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recommendations! Published in 2025 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.4c06591

Abstract: The CRISPR/Cas12a system has emerged as a powerful tool in biosensing due to its unique trans-cleavage activity. This study conducted an in-depth investigation of the modulatory capabilities of this system, particularly focusing on the 5'-end… read more here.

Keywords: system; crispr cas12a; activator strand; strand ... See more keywords
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Mapping the resources and approaches facilitating computer-aided synthesis planning

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recommendations! Published in 2020 at "Organic chemistry frontiers"

DOI: 10.1039/d0qo00946f

Abstract: Despite continuously significant breakthroughs in academia, organic synthesis remains the rate-limiting step everywhere, especially in a research environment where budget, manpower, and materials are increasingly restricted. Computer-aided synthesis planning (CASP) is a promising area of… read more here.

Keywords: casp; computer aided; chemistry; aided synthesis ... See more keywords

926. Shorter. Safer. Better. Pledge Campaign to Increase Uptake of Shortest Effective Durations of Antimicrobial Therapy

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recommendations! Published in 2022 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofac492.771

Abstract: Abstract Background Patients often receive longer-than-needed antimicrobial treatment for common infections, when a shorter duration would be equally effective. To promote use of evidence-based durations, the University of North Carolina Medical Center’s (MC) Carolina Antimicrobial… read more here.

Keywords: time; pledge campaign; bps; pledge ... See more keywords

Risk factors associated with clinical adjacent segment pathology following multi-level cervical fusion surgery

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recommendations! Published in 2018 at "Medicine"

DOI: 10.1097/md.0000000000013480

Abstract: Abstract Few clinical studies investigate risk factors associated with clinical adjacent segment pathology (CASP) following multi-level cervical fusion surgery. The aim is to record the incidence of postoperative CASP in patients after at least 2… read more here.

Keywords: risk; surgery; casp; multi level ... See more keywords

Effect of bisoprolol on central aortic systolic pressure in Chinese hypertensive patients after the initial dose and long term treatment.

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recommendations! Published in 2021 at "Bosnian journal of basic medical sciences"

DOI: 10.17305/bjbms.2021.6483

Abstract: We conducted a prospective open-label cohort study with the aim of examining the effects of the highly β1-selective agent bisoprolol on central aortic systolic pressure (CASP) after the first dose and after 6 weeks' treatment… read more here.

Keywords: first dose; casp; treatment; central aortic ... See more keywords

Hepatoprotective Activity of Red Ginger Extract on Acetaminophen-induced Liver Injury Models in HepG2 Cells

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recommendations! Published in 2025 at "Annals of African Medicine"

DOI: 10.4103/aam.aam_91_24

Abstract: Introduction: The liver is a major organ that plays a crucial role in detoxifying drugs; however, exposure to hepatotoxic drugs can lead to liver damage. Some research indicates that Zingiber officinale, commonly known as red… read more here.

Keywords: ginger extract; hepg2 cells; red ginger; rge ... See more keywords