Antidepressant Effect of Paeoniflorin Is Through Inhibiting Pyroptosis CASP-11/GSDMD Pathway
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Neurobiology"
DOI: 10.1007/s12035-020-02144-5
Abstract: Nod-like receptor protein 3 (NLRP3)-associated neuroinflammation mediated by activated microglia is involved in the pathogenesis of depression. The role of the pore-forming protein gasdermin D (GSDMD), a newly identified pyroptosis executioner downstream of NLRP3 inflammasome… read more here.
Keywords: depression; casp; paeoniflorin; pyroptosis ... See more keywords
Behavioral, molecular and physiological responses of embryo-larval zebrafish exposed to types I and II pyrethroids.
Sign Up to like & getrecommendations! Published in 2019 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2018.12.026
Abstract: Pyrethroids are potent neurotoxicants that may elicit multiple pathways of toxicity in non-target organisms. Comparative studies on the mechanistic and developmental effects of types I and II pyrethroids against non-target aquatic species are limited. This… read more here.
Keywords: embryo larval; casp; types pyrethroids; non target ... See more keywords
Mapping the resources and approaches facilitating computer-aided synthesis planning
Sign Up to like & getrecommendations! Published in 2020 at "Organic chemistry frontiers"
DOI: 10.1039/d0qo00946f
Abstract: Despite continuously significant breakthroughs in academia, organic synthesis remains the rate-limiting step everywhere, especially in a research environment where budget, manpower, and materials are increasingly restricted. Computer-aided synthesis planning (CASP) is a promising area of… read more here.
Keywords: casp; computer aided; chemistry; aided synthesis ... See more keywords
926. Shorter. Safer. Better. Pledge Campaign to Increase Uptake of Shortest Effective Durations of Antimicrobial Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofac492.771
Abstract: Abstract Background Patients often receive longer-than-needed antimicrobial treatment for common infections, when a shorter duration would be equally effective. To promote use of evidence-based durations, the University of North Carolina Medical Center’s (MC) Carolina Antimicrobial… read more here.
Keywords: time; pledge campaign; bps; pledge ... See more keywords
Risk factors associated with clinical adjacent segment pathology following multi-level cervical fusion surgery
Sign Up to like & getrecommendations! Published in 2018 at "Medicine"
DOI: 10.1097/md.0000000000013480
Abstract: Abstract Few clinical studies investigate risk factors associated with clinical adjacent segment pathology (CASP) following multi-level cervical fusion surgery. The aim is to record the incidence of postoperative CASP in patients after at least 2… read more here.
Keywords: risk; surgery; casp; multi level ... See more keywords
Effect of bisoprolol on central aortic systolic pressure in Chinese hypertensive patients after the initial dose and long term treatment.
Sign Up to like & getrecommendations! Published in 2021 at "Bosnian journal of basic medical sciences"
DOI: 10.17305/bjbms.2021.6483
Abstract: We conducted a prospective open-label cohort study with the aim of examining the effects of the highly β1-selective agent bisoprolol on central aortic systolic pressure (CASP) after the first dose and after 6 weeks' treatment… read more here.
Keywords: first dose; casp; treatment; central aortic ... See more keywords