Apoptosis Following Cortical Spreading Depression in Juvenile Rats
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0642-z
Abstract: Repetitive cortical spreading depression (CSD) can lead to cell death in immature brain tissue. Caspases are involved in neuronal cell death in several CSD-related neurological disorders, such as stroke and epilepsy. Yet, whether repetitive CSD… read more here.
Keywords: caspase; tissue; caspase caspase; repetitive csd ... See more keywords
Shuttling SLC2A4RG is regulated by 14-3-3θ to modulate cell survival via caspase-3 and caspase-6 in human glioma
Sign Up to like & getrecommendations! Published in 2019 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2019.01.030
Abstract: Background Glioma is the most common and aggressive primary brain tumor with polygenic susceptibility. The cytoplasmic/nuclear shuttling protein, SLC2A4RG (SLC2A4 regulator), has been identified in the 20q13.33 region influencing glioma susceptibility by genome-wide association studies… read more here.
Keywords: human glioma; cell; glioma; caspase caspase ... See more keywords
Caspase-1 Is an Apical Caspase Leading to Caspase-3 Cleavage in the AIM2 Inflammasome Response, Independent of Caspase-8.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2017.10.028
Abstract: Canonical inflammasomes are multiprotein complexes that can activate both caspase-1 and caspase-8. Caspase-1 drives rapid lysis of cells by pyroptosis and maturation of interleukin (IL)-1β and IL-18. In caspase-1-deficient cells, inflammasome formation still leads to… read more here.
Keywords: caspase; death; aim2 inflammasome; cleavage ... See more keywords
The effect of increased ambient temperature on Hsp70, superoxide dismutase, nitric oxide, malondialdehyde, and caspase activity in relation to the intrinsic and extrinsic apoptosis pathway of broiler blood cells.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of thermal biology"
DOI: 10.1016/j.jtherbio.2022.103211
Abstract: The objective of this study was to examine the effect of increased ambient temperature on Hsp70 expression, superoxide dismutase (SOD) activity, nitric oxide (NO), malondialdehyde (MDA), caspase 8, caspase 9 and caspase 3 in relation… read more here.
Keywords: caspase; activity; caspase caspase; temperature ... See more keywords
Mycobacterium fortuitum-induced ER-Mitochondrial calcium dynamics promotes calpain/caspase-12/caspase-9 mediated apoptosis in fish macrophages
Sign Up to like & getrecommendations! Published in 2018 at "Cell Death Discovery"
DOI: 10.1038/s41420-018-0034-9
Abstract: Mycobacterium fortuitum is a natural fish pathogen. It induces apoptosis in headkidney macrophages (HKM) of catfish, Clarias sp though the mechanism remains largely unknown. We observed M. fortuitum triggers calcium (Ca2+) insult in the sub-cellular… read more here.
Keywords: caspase; fortuitum; mycobacterium fortuitum; calpain caspase ... See more keywords
AB0049 Evaluation of caspase-3, caspase-9, caspase-14 and pannexin-1 levels in behÇet’s disease
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.3897
Abstract: Background Behçet’s disease (BD) is a rheumatic disease in which various systemic findings such as especially recurrent oral afts, and genital ulcers, eye involvement, skin lesions, gastrointestinal involvement, neurological involvement, vascular involvement and arthritis can… read more here.
Keywords: caspase; pannexin levels; group; disease ... See more keywords
The role of heme oxygenase-1 (HO-1) in the regulation of inflammatory reaction, neuronal cell proliferation and apoptosis in rats after intracerebral hemorrhage (ICH)
Sign Up to like & getrecommendations! Published in 2017 at "Neuropsychiatric Disease and Treatment"
DOI: 10.2147/ndt.s120496
Abstract: Objective To investigate the role of heme oxygenase-1 (HO-1) in the regulation of inflammatory reaction, neuronal cell proliferation and apoptosis in rats after intracerebral hemorrhage (ICH). Methods Thirty-six adult Sprague Dawley (SD) male rats were… read more here.
Keywords: caspase; apoptosis; caspase caspase; expression ... See more keywords
Chrysin inhibits propagation of HeLa cells by attenuating cell survival and inducing apoptotic pathways.
Sign Up to like & getrecommendations! Published in 2021 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202103_25253
Abstract: OBJECTIVE Chrysin, one of the main active constituents of flavonoids, is known for demonstrating protective effects against various types of cancer including cervical cancer. The aim of this study was to determine apoptosis induction and… read more here.
Keywords: caspase caspase; chrysin; hela cells; cell ... See more keywords
Non-Canonical Roles of Apoptotic Caspases in the Nervous System
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.840023
Abstract: Caspases are a family of cysteine proteases that predominantly cleave their substrates after aspartic acid residues. Much of what we know of caspases emerged from investigation a highly conserved form of programmed cell death called… read more here.
Keywords: caspase; canonical roles; apoptotic caspases; caspase caspase ... See more keywords
CircHIPK3 Promotes Pyroptosis in Acinar Cells Through Regulation of the miR-193a-5p/GSDMD Axis
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2020.00088
Abstract: Acute pancreatitis (AP), especially severe acute pancreatitis (SAP), is an extremely dangerous illness with a high mortality rate. Pyroptotic cells release their cellular contents and inflammatory factors, aggravating the inflammatory response. Pyroptosis may be the… read more here.
Keywords: pyroptosis; caspase caspase; mir 193a; circhipk3 ... See more keywords
Caspase-3 Inhibition Attenuates the Cytopathic Effects of EV71 Infection
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2018.00817
Abstract: Previous studies demonstrate that human enterovirus 71 (EV71), a primary causative agent for hand, foot, and mouth disease, activates caspase-3 through the non-structural viral 3C protein to induce host cell apoptosis; however, until now it… read more here.
Keywords: caspase; inhibition; caspase caspase; ev71 infection ... See more keywords