Caspase-1 inhibition by YVAD generates tregs pivoting IL-17 to IL-22 response in β-glucan induced airway inflammation
Sign Up to like & getrecommendations! Published in 2022 at "Immunopharmacology and Immunotoxicology"
DOI: 10.1080/08923973.2022.2043899
Abstract: Abstract Background During Aspergillus fumigatus mediated lung inflammation, NLRP3 inflammasome is rapidly activated that aggravates IL-1β production contributing to lung inflammation. Previously, we have shown the protective role of SYK-1 inhibition in inhibiting inflammasome activation… read more here.
Keywords: caspase inhibition; lung inflammation; glucan induced; inhibition ... See more keywords
Caspase-3 Inhibition Attenuates the Cytopathic Effects of EV71 Infection
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DOI: 10.3389/fmicb.2018.00817
Abstract: Previous studies demonstrate that human enterovirus 71 (EV71), a primary causative agent for hand, foot, and mouth disease, activates caspase-3 through the non-structural viral 3C protein to induce host cell apoptosis; however, until now it… read more here.
Keywords: caspase; inhibition; caspase caspase; ev71 infection ... See more keywords
Caspase Inhibition as a Possible Therapeutic Strategy for Pemphigus Vulgaris: A Systematic Review of Current Evidence
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11020314
Abstract: Simple Summary Pemphigus vulgaris is a potentially fatal disease characterised by blister formation affecting the skin and mouth. The mechanisms of blister formation may involve a biological process called apoptosis—a type of cell death—and some… read more here.
Keywords: caspase inhibition; caspase; pemphigus vulgaris; vivo ... See more keywords