Myeloid caspase-8 restricts RIPK3-dependent proinflammatory IL-1β production and CD4 T cell activation in autoimmune demyelination
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DOI: 10.1073/pnas.2117636119
Abstract: Significance Autoimmune demyelination is driven by pathogenic T cells and inflammatory myeloid cells. How myeloid and T cells functionally interact and contribute to inflammatory demyelinating disease, such as multiple sclerosis, remains incompletely understood. This study… read more here.
Keywords: myeloid caspase; myeloid cells; production; autoimmune demyelination ... See more keywords