Integration of diverse DNA substrates by a casposase can be targeted to R-loops in vitro by its fusion to Cas9
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DOI: 10.1042/bsr20203595
Abstract: Abstract CRISPR systems build adaptive immunity against mobile genetic elements by DNA capture and integration catalysed by Cas1–Cas2 protein complexes. Recent studies suggested that CRISPR repeats and adaptation module originated from a novel type of… read more here.
Keywords: dna integration; casposase; dna; fusion ... See more keywords