Tojapride prevents CaSR‐mediated NLRP3 inflammasome activation in oesophageal epithelium irritated by acidic bile salts
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DOI: 10.1111/jcmm.14631
Abstract: Impairment of the oesophageal epithelium in patients with reflux oesophagitis (RE) is a cytokine‐mediated injury rather than a chemical burn. The present study was conducted to explore CaSR/NLRP3 inflammasome pathway activation and cytokines IL‐1β and… read more here.
Keywords: casr mediated; acidic bile; activation; nlrp3 inflammasome ... See more keywords