Use of live Variola virus to determine whether CAST/EiJ mice are a suitable surrogate animal model for human smallpox.
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DOI: 10.1016/j.virusres.2019.197772
Abstract: Numerous animal models of systemic orthopoxvirus disease have been developed to evaluate therapeutics against variola virus (VARV), the causative agent of smallpox. These animal models do not resemble the disease presentation in human smallpox and… read more here.
Keywords: smallpox; model; eij mice; cast eij ... See more keywords