Rapid reduction of extremely high kappa free light chains in a patient with myeloma cast nephropathy
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Apheresis"
DOI: 10.1002/jca.21619
Abstract: This report describes a patient with light chain myeloma and acute renal injury. Serum kappa free light chain (FLC) was extremely elevated, >33,000 mg/dL. Treatment with therapeutic plasma exchange (TPE) started day 2 for biopsy‐confirmed… read more here.
Keywords: cast nephropathy; kappa free; free light; tpe ... See more keywords
Myeloma light chain cast nephropathy, a review
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Nephrology"
DOI: 10.1007/s40620-018-0492-4
Abstract: Multiple Myeloma is a plasma cell proliferative disorder that commonly involves the kidney. Renal impairment is a serious complication during the course of the disease that is associated with increased morbidity and mortality. Light chain… read more here.
Keywords: chain cast; cast nephropathy; myeloma; light chain ... See more keywords
Paraneoplastic REG1α Cast Nephropathy Associated With Mixed Acinar-Neuroendocrine Carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Kidney International Reports"
DOI: 10.1016/j.ekir.2021.01.026
Abstract: Samih H. Nasr, Surendra Dasari, Jason D. Theis, Julie A. Vrana, Samar M. Said, Paul J. Kurtin, Ellen D. McPhail and David George Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA; Department… read more here.
Keywords: reg1 cast; medicine; cast nephropathy; nephropathy associated ... See more keywords
Cholemic or Bile Cast Nephropathy in a Child with Liver Failure.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of clinical and experimental hepatology"
DOI: 10.1016/j.jceh.2017.05.006
Abstract: Cholemic or bile cast nephropathy is an under-reported entity characterized by acute renal dysfunction in patients with hepatic insult. Limited literature is available regarding its clinical presentation, pathogenesis and prognosis. We hereby present a pediatric… read more here.
Keywords: cholemic bile; cast nephropathy; liver failure; bile cast ... See more keywords
Cholangitis Lenta Causing Bile Cast Nephropathy: A Unique Model of Hepatorenal Failure in Sepsis
Sign Up to like & getrecommendations! Published in 2018 at "Fetal and Pediatric Pathology"
DOI: 10.1080/15513815.2018.1520945
Abstract: Abstract Introduction: Inadequate perfusion and abnormal cellular metabolism are among the mechanisms of organ dysfunction in sepsis. Concomitant hepatorenal failure during the late phase of sepsis is poorly understood. Case report: The autopsy of a… read more here.
Keywords: sepsis; cast nephropathy; bile cast; hepatorenal failure ... See more keywords
Bile Cast Nephropathy in Cirrhotic Patients: Effects of Chronic Hyperbilirubinemia
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Clinical Pathology"
DOI: 10.1093/ajcp/aqx030
Abstract: Objectives The aim of this study was to determine the prevalence of bile cast nephropathy (BCN) in autopsied cirrhotic patients and to correlate BCN with clinical and laboratory data to direct attention to this underrecognized… read more here.
Keywords: cast nephropathy; etiology; cirrhotic patients; bile cast ... See more keywords
Enhanced elimination of cyclophosphamide by high cut-off haemodialysis: single-dose pharmacokinetics in a patient with cast nephropathy
Sign Up to like & getrecommendations! Published in 2018 at "BMJ Case Reports"
DOI: 10.1136/bcr-2017-221735
Abstract: High cut-off (HCO) haemodialysis removes free light chains in patients with multiple myeloma. This is possible as HCO dialysers allow clearance of molecules up to a molecular weight of 65 kDa. In contrast, high-flux dialysers, which… read more here.
Keywords: cast nephropathy; haemodialysis; high cut; cyclophosphamide ... See more keywords
Light chain proximal tubulopathy with cast nephropathy in monoclonal gammopathy of renal significance
Sign Up to like & getrecommendations! Published in 2020 at "BMJ Case Reports"
DOI: 10.1136/bcr-2020-234361
Abstract: Kidney tubular disorders due to monoclonal immunoglobulin light chains are common manifestations of B-cell neoplasm. Cast nephropathy (CN) is the most frequent type of these disorders and may present with acute kidney injury (AKI) due… read more here.
Keywords: cast nephropathy; proximal tubulopathy; light; chain proximal ... See more keywords
Unusual cause of light chain cast nephropathy
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2021-246777
Abstract: Acute kidney injury due to light chain cast nephropathy is increasingly recognised in patients with haematological malignancies; however, the management and prognosis of this disease remain poorly understood. We describe a case of a 78-year-old… read more here.
Keywords: cast nephropathy; light chain; unusual cause; chain cast ... See more keywords
Clinicopathologic predictors of renal outcomes in light chain cast nephropathy: A multicenter retrospective study.
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DOI: 10.1182/blood.2019003807
Abstract: Light chain cast nephropathy (LCCN) in multiple myeloma often leads to severe and poorly reversible acute kidney injury. Severe renal impairment influences the allocation of chemotherapy, its tolerability, and affects patient survival. Whether renal biopsy… read more here.
Keywords: cast nephropathy; response; study; chain cast ... See more keywords
Vancomycin-Associated Cast Nephropathy.
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DOI: 10.1681/asn.2016080867
Abstract: Vancomycin is a widely prescribed antibiotic, but the exact nature of vancomycin-associated nephrotoxicity is unclear, in particular when considering the frequent coadministration of aminoglycosides. We describe here the initial case of a 56-year-old woman with… read more here.
Keywords: vancomycin; cast nephropathy; nephrology; vancomycin associated ... See more keywords