Visualizing the interaction of Acanthamoeba castellanii with human retinal epithelial cells by spontaneous Raman and CARS imaging
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Raman Spectroscopy"
DOI: 10.1002/jrs.5296
Abstract: Improved understanding of the mechanism of nutrient's uptake can enable targeted manipulation of nutrient sensing pathways in medically important pathogens to a greater degree than is currently possible. In this context, we present the use… read more here.
Keywords: human retinal; castellanii; acanthamoeba castellanii; spontaneous raman ... See more keywords
Transcriptional analysis of flagellar and putative virulence genes of Arcobacter butzleri as an endocytobiont of Acanthamoeba castellanii
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Microbiology"
DOI: 10.1007/s00203-019-01678-0
Abstract: Arcobacter butzleri is an emerging foodborne zoonotic pathogen that has been isolated from environmental water sources. This pathogen establishes in vitro endosymbiotic relationships with Acanthamoeba castellanii, a free-living amoeba found in environmental matrices such as… read more here.
Keywords: virulence genes; castellanii; putative virulence; arcobacter butzleri ... See more keywords
Type 1 Fimbriae and Motility Play a Pivotal Role During Interactions of Salmonella typhimurium with Acanthamoeba castellanii (T4 Genotype)
Sign Up to like & getrecommendations! Published in 2020 at "Current Microbiology"
DOI: 10.1007/s00284-019-01868-5
Abstract: Amoebic bacterial interactions are the most ancient form of host pathogen interactions. Here, we investigate the fate of Salmonella typhimurium and Acanthamoeba castellanii T4 genotype upon mutual interactions in a nutrition free environment. The role… read more here.
Keywords: type fimbriae; castellanii; typhimurium; role ... See more keywords
Antiamoebic activity of 3-aryl-6,7-dimethoxyquinazolin-4(3H)-one library against Acanthamoeba castellanii
Sign Up to like & getrecommendations! Published in 2020 at "Parasitology Research"
DOI: 10.1007/s00436-020-06710-7
Abstract: Acanthamoeba castellanii is a free-living amoeba which can cause a blinding keratitis and fatal granulomatous amoebic encephalitis. The treatment of Acanthamoeba infections is challenging due to formation of cyst. Quinazolinones are medicinally important scaffold against… read more here.
Keywords: aryl dimethoxyquinazolin; castellanii; acanthamoeba castellanii; dimethoxyquinazolin one ... See more keywords
The amoebicidal activity of three substances derived from benzothiazole on Acanthamoeba castellanii cysts and trophozoites and its cytotoxic potentials.
Sign Up to like & getrecommendations! Published in 2021 at "Acta tropica"
DOI: 10.1016/j.actatropica.2021.105981
Abstract: Acanthamoeba species are free-living amoebae isolated from many ecological areas such as swimming pools, dams, lakes, soil, and air filters. These amoebae are usually causing granulomatous amebic encephalitis and amebic keratitis in immunosuppressive individuals. In… read more here.
Keywords: active substances; three substances; substances derived; acanthamoeba castellanii ... See more keywords
Legionella pneumophila decreases velocity of Acanthamoeba castellanii.
Sign Up to like & getrecommendations! Published in 2017 at "Experimental parasitology"
DOI: 10.1016/j.exppara.2017.07.013
Abstract: Acanthamoeba castellanii is a free-living amoeba commonly found in aquatic environment. It feeds on bacteria even if some bacteria resist amoebal digestion. Thus, A. castellanii is described as a Trojan horse able to harbor pathogenic bacteria.… read more here.
Keywords: castellanii; velocity; acanthamoeba castellanii; legionella pneumophila ... See more keywords
Repositioning of guanabenz in conjugation with gold and silver nanoparticles against pathogenic amoebae Acanthamoeba castellanii and Naegleria fowleri.
Sign Up to like & getrecommendations! Published in 2019 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.9b00263
Abstract: Brain-eating amoebae cause devastating infections of central nervous system in humans, having a mortality rate of 95%. There are limited effective therapeutic options available clinically for treating granulomatous amoebic encephalitis and primary amoebic meningoencephalitis caused… read more here.
Keywords: silver nanoparticles; castellanii; gold silver; guanabenz ... See more keywords
Novel Antiamoebic Tyrocidine-Derived Peptide against Brain-Eating Amoebae
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c01614
Abstract: Acanthamoeba castellanii (A. castellanii) can cause Acanthamoeba keratitis, a sight-threatening infection, as well as a fatal brain infection termed granulomatous amoebic encephalitis, mostly in immunocompromised individuals. In contrast, Naegleria fowleri (N. fowleri) causes a deadly… read more here.
Keywords: castellanii fowleri; castellanii; tyrocidine derived; derived peptide ... See more keywords
Survival of Bordetella bronchiseptica in Acanthamoeba castellanii
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00487-23
Abstract: The pathogenic bacterium Bordetella bronchiseptica, which causes respiratory diseases in various mammals, exhibits distinct Bvg+ and Bvg− phenotypes. The former represents the virulent phase, in which the bacteria express a set of virulence factors, while… read more here.
Keywords: bordetella bronchiseptica; bvg phase; bronchiseptica; castellanii ... See more keywords
Legionella pneumophila Infection Rewires the Acanthamoeba castellanii Transcriptome, Highlighting a Class of Sirtuin Genes
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2020.00428
Abstract: Legionella pneumophila is an environmental bacterium that has evolved to survive predation by soil and water amoebae such as Acanthamoeba castellanii, and this has inadvertently led to the ability of L. pneumophila to survive and… read more here.
Keywords: castellanii; pneumophila infection; infection; acanthamoeba castellanii ... See more keywords
Antiamoebic Activity of Imidazothiazole Derivatives against Opportunistic Pathogen Acanthamoeba castellanii
Sign Up to like & getrecommendations! Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11091183
Abstract: We examined the antiamoebic effect of several imidazothiazole derivatives on Acanthamoeba castellanii of the T4 genotype. Trypan blue exclusion assays and haemocytometer counting were used to determine the reduction in A. castellanii trophozoite proliferation, in… read more here.
Keywords: antiamoebic activity; castellanii; imidazothiazole derivatives; compounds 1zb ... See more keywords