Vms1: A Cytosolic CAT-Tailing Antagonist to Protect Mitochondria.
Sign Up to like & getrecommendations! Published in 2018 at "Trends in cell biology"
DOI: 10.1016/j.tcb.2017.11.003
Abstract: In eukaryotes, a cytosolic ribosome quality control complex recycles erroneously stalled ribosomes and modifies faulty nascent chains by ubiquitination and by C-terminal Ala- and Thr-extension (CAT-tailing). Reported recently in Cell, Izawa et al. identify cytosolic… read more here.
Keywords: cytosolic cat; vms1 cytosolic; tailing antagonist; cat tailing ... See more keywords
In vitro analysis of RQC activities provides insights into the mechanism and function of CAT tailing
Sign Up to like & getrecommendations! Published in 2017 at "eLife"
DOI: 10.7554/elife.27949
Abstract: Ribosomes can stall during translation due to defects in the mRNA template or translation machinery, leading to the production of incomplete proteins. The Ribosome-associated Quality control Complex (RQC) engages stalled ribosomes and targets nascent polypeptides… read more here.
Keywords: analysis rqc; rqc activities; cat tailing; vitro analysis ... See more keywords