Molecular docking-aided identification of small molecule inhibitors targeting β-catenin-TCF4 interaction
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DOI: 10.1016/j.isci.2021.102544
Abstract: Summary Here we report a molecular docking-based approach to identify small molecules that can target the β-catenin (β-cat)-TCF4 protein-protein interaction (PPI), a key effector complex for nuclear Wnt signaling activity. Specifically, we developed and optimized… read more here.
Keywords: tcf4 interaction; tcf4; cat tcf4; interaction ... See more keywords