Flightless I is a catabolic factor of chondrocytes that promotes hypertrophy and cartilage degeneration in osteoarthritis
Sign Up to like & getrecommendations! Published in 2021 at "iScience"
DOI: 10.1016/j.isci.2021.102643
Abstract: Summary Synovial macrophages that are activated by cartilage fragments initiate synovitis, a condition that promotes hypertrophic changes in chondrocytes leading to cartilage degeneration in OA. In this study, we analyzed the molecular response of chondrocytes… read more here.
Keywords: flightless catabolic; catabolic factor; cartilage degeneration; factor chondrocytes ... See more keywords
FasL is a catabolic factor in alveolar bone homeostasis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of clinical periodontology"
DOI: 10.1111/jcpe.13750
Abstract: AIM Fas ligand (FasL) belongs to the tumor necrosis factor (TNF) superfamily regulating bone turnover, inflammation, and apoptosis. The appendicular and axial skeleton phenotype of mature Faslgld mice was reported. The impact of FasL on… read more here.
Keywords: alveolar bone; bone; factor alveolar; fasl catabolic ... See more keywords