Identification of a novel inhibitor of catabolite control protein A from Staphylococcus aureus.
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DOI: 10.1021/acsinfecdis.9b00465
Abstract: Catabolite control protein A is a highly conserved transcriptional regulator in Gram-positive bacteria. Herein, we report a specific small-molecule inhibitor of Staphylococcus aureus CcpA (SaCcpA). The compound abrogates the regulatory function of SaCcpA, resulting in… read more here.
Keywords: control protein; catabolite control; staphylococcus aureus; inhibitor ... See more keywords