A bidirectional synthesis of spiroacetals via Rh(ii)-catalysed C-H insertion.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc00459a
Abstract: Acyclic methylene acetals bearing two diazoester subunits have been converted to [5,5]-spiroacetals via bidirectional C-H insertion under Rh(ii) catalysis. Using a chiral Rh(ii) catalyst, the major diastereomer can be produced in high enantiomeric excess (89%). read more here.
Keywords: bidirectional synthesis; insertion; via catalysed; catalysed insertion ... See more keywords