Disruption of redox catalytic functions of peroxiredoxin-thioredoxin complex in Mycobacterium tuberculosis H37Rv using small interface binding molecules
Sign Up to like & getrecommendations! Published in 2017 at "Computational biology and chemistry"
DOI: 10.1016/j.compbiolchem.2016.12.013
Abstract: Mycobacterium tuberculosis has distinctive ability to detoxify various microbicidal superoxides and hydroperoxides via a redox catalytic cycle involving thiol reductants of peroxiredoxin (Prx) and thioredoxin (Trx) systems which has conferred on it resistance against oxidative… read more here.
Keywords: interface binding; trx; catalytic functions; redox catalytic ... See more keywords
Eph receptor signalling: from catalytic to non-catalytic functions
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DOI: 10.1038/s41388-019-0931-2
Abstract: Eph receptors, the largest subfamily of receptor tyrosine kinases, are linked with proliferative disease, such as cancer, as a result of their deregulated expression or mutation. Unlike other tyrosine kinases that have been clinically targeted,… read more here.
Keywords: receptor signalling; non catalytic; eph receptor; eph receptors ... See more keywords