'Negative' and 'positive catalysis': complementary principles that shape the catalytic landscape of enzymes.
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DOI: 10.1016/j.cbpa.2018.09.013
Abstract: Our understanding of enzyme catalysis is dominated by transition state theory. According to this concept, an enzymatic reaction is guided along a desired reaction coordinate through the stabilization of favorable transition state. But how much… read more here.
Keywords: landscape enzymes; catalytic landscape; catalysis; enzyme catalysis ... See more keywords