Insights into substrate behavior in a solvent-free protein liquid to rationalize its reduced catalytic rate
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DOI: 10.1039/d2ra00666a
Abstract: When proteins are engineered with a polymer surfactant coating on their surface, they can form a liquid phase by themselves, without the need for a solvent, such as, say, water. However, such solvent-free protein liquids… read more here.
Keywords: catalytic rate; reduced catalytic; solvent free; free protein ... See more keywords
Micellar Choline-Acetyltransferase Complexes Exhibit Ultra-Boosted Catalytic Rate for Acetylcholine Synthesis—Mechanistic Insights for Development of Acetylcholine-Enhancing Micellar Nanotherapeutics
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms252413602
Abstract: Choline-acetyltransferase (ChAT) is the key cholinergic enzyme responsible for the biosynthesis of acetylcholine (ACh), a crucial signaling molecule with both canonical neurotransmitter function and auto- and paracrine signaling activity in non-neuronal cells, such as lymphocytes… read more here.
Keywords: rate; choline acetyltransferase; acetylcholine; catalytic rate ... See more keywords