Catalytic Reductive Functionalization of Tertiary Amides using Vaska’s Complex: Synthesis of Complex Tertiary Amine Building Blocks and Natural Products
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DOI: 10.1021/acscatal.0c02377
Abstract: The tertiary amide is a ubiquitous functional group and plays an irreplaceable role in medicinal chemistry. Its robust nature has meant—in the past—that selective manipulation of this motif remaine... read more here.
Keywords: using vaska; reductive functionalization; amides using; functionalization tertiary ... See more keywords
Catalytic Reductive Vinylidene Transfer Reactions.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b05901
Abstract: Methylenecyclopropanes are important synthetic intermediates that possess strain energies exceeding those of saturated cyclopropanes by >10 kcal/mol. This report describes a catalytic reductive methylenecyclopropanation reaction of simple olefins, utilizing 1,1-dichloroalkenes as vinylidene precursors. The reaction… read more here.
Keywords: vinylidene transfer; reductive vinylidene; catalytic reductive; transfer reactions ... See more keywords
Continuous flow heterogeneous catalytic reductive aminations under aqueous micellar conditions enabled by an oscillatory plug flow reactor
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DOI: 10.1039/d1gc02039k
Abstract: An oscillatory plug flow reactor that combines active and passive mixing enables heterogeneous catalytic reductive aminations under aqueous micellar conditions in an inherently scalable manner. read more here.
Keywords: oscillatory plug; plug flow; heterogeneous catalytic; flow reactor ... See more keywords