The GlcN6P cofactor plays multiple catalytic roles in the glmS ribozyme.
Sign Up to like & getrecommendations! Published in 2017 at "Nature chemical biology"
DOI: 10.1038/nchembio.2300
Abstract: RNA enzymes (ribozymes) have remarkably diverse biological roles despite having limited chemical diversity. Protein enzymes enhance their reactivity through recruitment of cofactors; likewise, the naturally occurring glmS ribozyme uses the glucosamine-6-phosphate (GlcN6P) organic cofactor for… read more here.
Keywords: glms ribozyme; glcn6p cofactor; catalytic roles; plays multiple ... See more keywords
DNMT1: catalytic and non-catalytic roles in different biological processes.
Sign Up to like & getrecommendations! Published in 2022 at "Epigenomics"
DOI: 10.2217/epi-2022-0035
Abstract: DNMT1 is the main enzyme that uses the information on DNA methylation patterns in the parent strand and methylates the daughter strand in freshly replicated hemimethylated DNA. It is widely known that DNMT1 is a… read more here.
Keywords: different biological; non catalytic; dnmt1 catalytic; catalytic roles ... See more keywords
Non-Catalytic Roles of the Topoisomerase IIα C-Terminal Domain
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms18112438
Abstract: DNA Topoisomerase IIα (Topo IIα) is a ubiquitous enzyme in eukaryotes that performs the strand passage reaction where a double helix of DNA is passed through a second double helix. This unique reaction is critical… read more here.
Keywords: roles topoisomerase; terminal domain; non catalytic; catalytic roles ... See more keywords