A Catalytic and Selective Scissoring Molecular Tool for Quadruplex Nucleic Acids
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.8b05337
Abstract: A copper complex embedded in the structure of a water-soluble naphthalene diimide has been designed to bind and cleave G-quadruplex DNA. We describe the properties of this ligand, including its catalytic activity in the generation… read more here.
Keywords: quadruplex nucleic; selective scissoring; scissoring molecular; catalytic selective ... See more keywords
Dual pH-triggered catalytic selective Mn clusters for cancer radiosensitization and radioprotection.
Sign Up to like & getrecommendations! Published in 2019 at "Nanoscale"
DOI: 10.1039/c9nr08192e
Abstract: Hypoxia is known to be a common feature within many types of solid tumors, which is closely related to the limited efficacy of radiotherapy. Meanwhile, due to the non-discriminatory killing effect of both normal and… read more here.
Keywords: selective clusters; dual triggered; clusters cancer; triggered catalytic ... See more keywords