Catalytic (3 + 2) umpolung annulations of α-thioacyl carbenes with aryl isothiocyanates.
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DOI: 10.1039/d2cc02882d
Abstract: 1,2,3-Thiadiazoles serve as masked S-electrophilic thia-1,3-dipoles. Under rhodium/racemic BINAP catalysis, they undergo denitrogenative (3 + 2) umpolung transannulations with aryl isothiocyanates with inverse regioselectivity and excellent stereoselectivity, yielding N-aryl 3H-1,2-dithiol-(Z)-3-imines in a redox-neutral, step-efficient, and… read more here.
Keywords: catalytic umpolung; carbenes aryl; annulations thioacyl; aryl isothiocyanates ... See more keywords