TEMPO‐Catalyzed Aerobic Oxidative Coupling of Thiols for Metal‐Free Formation of S−N/S−S Bonds
Sign Up to like & getrecommendations! Published in 2017 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.201600588
Abstract: The catalytic synthesis of organic sulfenamides and disulfides has great significance and value in synthetic chemistry and bioscience. To establish a versatile and efficient technology for such reactions, we successfully developed a new aerobic oxidative… read more here.
Keywords: chemistry; aerobic oxidative; oxidative coupling; tempo catalyzed ... See more keywords
Palladium‐Catalyzed Aerobic Synthesis of Terminal Acetals from Vinylarenes Assisted by π‐Acceptor Ligands
Sign Up to like & getrecommendations! Published in 2017 at "ChemCatChem"
DOI: 10.1002/cctc.201601517
Abstract: Terminal acetals were synthesized from various vinylarenes and 1,2‐ or 1,3‐diols using a simple PdCl2(MeCN)2/methoxy‐p‐benzoquinone (MeOBQ)/CuCl catalyst system and 1 atm of O2 under mild reaction conditions by the anti‐Markovnikov nucleophilic attack of an oxygen nucleophile… read more here.
Keywords: aerobic synthesis; synthesis terminal; terminal acetals; palladium catalyzed ... See more keywords
Four-Component Reaction for the Synthesis of Indolizines by Copper-Catalyzed Aerobic Oxidative Dehydrogenative Aromatization
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201601272
Abstract: A one-pot, four-component reaction was developed for the synthesis of indolizines from pyridines, α-halide carbonyl compounds, primary amines, and maleic anhydride. The key step in this reaction involved the copper-catalyzed aerobic oxidative aromatization of a… read more here.
Keywords: four component; reaction; synthesis indolizines; component reaction ... See more keywords
Design and Development of Pd-Catalyzed Aerobic N-Demethylation Strategies for the Synthesis of Noroxymorphone in Continuous Flow Mode
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201601453
Abstract: Strategies for the generation of noroxymorphone from 14-hydroxymorphinone are presented. Noroxymorphone is the key intermediate in the synthesis of various opioid antagonists, including naloxone, naltrexone and nalmefene, as well as mixed agonists-antagonists like nalbuphine. The… read more here.
Keywords: development catalyzed; aerobic demethylation; design development; continuous flow ... See more keywords
ABNO-Catalyzed Aerobic Oxidative Synthesis of 2-Substituted 4H-3,1-Benzoxazines and Quinazolines
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201700384
Abstract: A new transition-metal-free 9-azabicyclo[3.3.1]nonan-N-oxyl (ABNO) catalyzed aerobic oxidative synthesis of 2-substituted 4H-3,1-benzoxazines and quinazolines has been developed through cascade reaction of aldehydes with 2-aminobenzyl alcohols and 2-aminobenzylamines, respectively. Under the optimal reaction conditions, the two… read more here.
Keywords: synthesis substituted; oxidative synthesis; abno catalyzed; aerobic oxidative ... See more keywords
I2-Catalyzed Aerobic α,β-Dehydrogenation and Deamination of Tertiary Alkylamines: Highly Selective Synthesis of Polysubstituted Pyrimidines via Hidden Acyclic Enamines.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c02001
Abstract: A novel and efficient entrance to the pyrimidine skeleton has been presented via the α,β-dehydrogenation and deamination of tertiary alkylamines. This I2-catalyzed dehydrogenative multicomponent procedure utilizes simple aldehydes to trap the hidden enamine intermediates and… read more here.
Keywords: dehydrogenation deamination; deamination tertiary; tertiary alkylamines; catalyzed aerobic ... See more keywords
Copper-Catalyzed Aerobic Selective Oxidation of Tetrahydrocarbolines.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c01059
Abstract: We report a safe and convenient open-flask copper-catalyzed selective oxidation/functionalization methodology for tetrahydrocarbolines and tetrahydro-β-carbolines that employs atmospheric O2 as the terminal oxidant. The system is applicable to oxidative rearrangement of tetrahydro-β-carbolines, tetrahydrocarboline oxidation to… read more here.
Keywords: oxidation; catalyzed aerobic; selective oxidation; aerobic selective ... See more keywords
Bioinspired o-Naphthoquinone-Catalyzed Aerobic Oxidation of Alcohols to Aldehydes and Ketones.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02037
Abstract: A biomimetic alcohol dehydrogenase (ADH)-like oxidation protocol was developed using an ortho-naphthoquinone catalyst in the presence of a catalytic amount of base. The developed organocatalytic aerobic oxidation protocol proceeds through the intramolecular 1,5-hydrogen atom transfer… read more here.
Keywords: oxidation; aerobic oxidation; catalyzed aerobic; oxidation protocol ... See more keywords
Copper-Catalyzed, Aerobic Synthesis of NH-Sulfonimidamides from Primary Sulfinamides and Secondary Amines.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02804
Abstract: NH-Sulfonimidamides are prepared by copper-catalyzed coupling of primary sulfinamides with secondary amines. Neither a ligand nor an additive is needed, and air is the terminal oxidant. The reactions occur at room temperature, show good functional… read more here.
Keywords: primary sulfinamides; catalyzed aerobic; sulfinamides secondary; secondary amines ... See more keywords
Cu-Catalyzed Aerobic Oxidative Sulfuration/Annulation Approach to Thiazoles via Multiple Csp3-H Bond Cleavage.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b00840
Abstract: A novel and practical Cu-catalyzed aerobic oxidative synthesis of thiazoles was developed. This chemistry for the first time achieved thiazole construction from simple aldehydes, amines, and element sulfur through multiple Csp3-H bond cleavage processes. Molecular… read more here.
Keywords: sulfuration annulation; multiple csp3; bond cleavage; csp3 bond ... See more keywords
Heterogeneously Catalyzed Aerobic Oxidation of Sulfides with a BaRuO3 Nanoperovskite.
Sign Up to like & getrecommendations! Published in 2018 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.8b05343
Abstract: A rhombohedral BaRuO3 nanoperovskite, which was synthesized by the sol-gel method using malic acid, could act as an efficient heterogeneous catalyst for the selective oxidation of various aromatic and aliphatic sulfides with molecular oxygen as… read more here.
Keywords: oxygen; oxidation; aerobic oxidation; heterogeneously catalyzed ... See more keywords