“Iron catalyzed alkynylation of thiohydantoins with terminal alkyne via cross-dehydrogenative coupling (CDC)”
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2021.153148
Abstract: Abstract Herein, A novel strategy for Iron(II)-catalyzed alkynylation of thiohydantoins with terminal alkyne has been firstly reported. Optimization study was carried out through various catalysts, oxidants and solvents. The merit of this strategy is illustrated… read more here.
Keywords: iron catalyzed; alkynylation thiohydantoins; terminal alkyne; catalyzed alkynylation ... See more keywords
Cu(I)-Catalyzed Alkynylation of Quinolones
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DOI: 10.1021/acs.orglett.2c00020
Abstract: Herein we report the first alkynylation of quinolones with terminal alkynes under mild reaction conditions. The reaction is catalyzed by Cu(I) salts in the presence of a Lewis acid, which is essential for the reactivity… read more here.
Keywords: methodology; catalyzed alkynylation; alkynylation quinolones;
Copper-Catalyzed Alkynylation of Hydrazides: An Easy Access to Functionalized Azadipeptides.
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DOI: 10.1021/acs.orglett.2c02625
Abstract: We report a copper-catalyzed alkynylation of azadipeptides using ethynylbenziodoxolone (EBX) reagents. Nonsymmetrical ynehydrazides could be obtained in 25-97% yield using azaglycine derivatives as nucleophiles. The transformation is compatible with most functional groups naturally occurring on… read more here.
Keywords: hydrazides easy; easy access; catalyzed alkynylation; alkynylation hydrazides ... See more keywords
Facilitating Ir-Catalyzed C–H Alkynylation with Electrochemistry: Anodic Oxidation-Induced Reductive Elimination
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DOI: 10.1021/acscatal.0c03207
Abstract: An electrochemical approach in promoting directed C-H alkynylation with terminal alkyne via iridium catalysis is reported. This work employed anodic oxidation of Ir(III) intermediate (characterized... read more here.
Keywords: alkynylation electrochemistry; facilitating catalyzed; electrochemistry; catalyzed alkynylation ... See more keywords