Mechanistic insights on DBU catalyzed β‐amination of nbs to chalcone driving by water: Multiple roles of water
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Computational Chemistry"
DOI: 10.1002/jcc.24700
Abstract: DFT calculations were conducted to pursue deeper understandings on the mechanism and the explicit role of trace water in the DBU‐catalyzed β‐amination of NBS to chalcone. Being different from previously proposed by Liang et al.,… read more here.
Keywords: nbs chalcone; water; dbu catalyzed; amination nbs ... See more keywords
Synthesis of optically active 3,3’-disubstituted biphenyl derivatives using palladium-catalyzed amination and their evaluation as enantioselective fluorescent detectors for amino alcohols and metal cations
Sign Up to like & getrecommendations! Published in 2020 at "Russian Chemical Bulletin"
DOI: 10.1007/s11172-020-2911-7
Abstract: The palladium-catalyzed amination was used to synthesize optically active 3,3’-diaminosubstituted biphenyl derivatives (in particular, macrocyclic derivatives) decorated with additional fluorophore groups (dansyl and 7-methoxycoumarin). The synthesized compounds were studied by spectroscopic methods (UV spectroscopy, fluorescence)… read more here.
Keywords: optically active; biphenyl derivatives; palladium catalyzed; amino alcohols ... See more keywords
Efficient synthesis of dibenzazepine lactams via a sequential Pd-catalyzed amination and aldol condensation reaction
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2019.151536
Abstract: Abstract A simple and efficient reaction was developed for the synthesis of dibenzazepine lactam derivatives. The core 7-membered azepine ring was formed by a stepwise sequence involving a palladium-catalyzed amination and an aldol condensation. read more here.
Keywords: synthesis dibenzazepine; amination aldol; reaction; catalyzed amination ... See more keywords
Transition Metal-Catalyzed C-H Amination: Scope, Mechanism, and Applications.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical reviews"
DOI: 10.1021/acs.chemrev.6b00644
Abstract: Catalytic transformation of ubiquitous C-H bonds into valuable C-N bonds offers an efficient synthetic approach to construct N-functionalized molecules. Over the last few decades, transition metal catalysis has been repeatedly proven to be a powerful… read more here.
Keywords: transition; catalyzed amination; transition metal; metal catalyzed ... See more keywords
A Mechanistic Study of the Cobalt(I)-Catalyzed Amination of Aryl Halides: Effects of Metal and Ligand.
Sign Up to like & getrecommendations! Published in 2022 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.2c02385
Abstract: Transition-metal-catalyzed amination of aryl halides is a useful approach for the synthesis of medicinal compounds, organic functional materials, and agrochemical compounds. A systematic DFT study has been performed to investigate the mechanism of the Co(I)-catalyzed… read more here.
Keywords: aryl halides; catalyzed amination; amination; amination aryl ... See more keywords
Palladium-Catalyzed Amination of Aryl Sulfoxides.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b00060
Abstract: Amination of diaryl sulfoxides with anilines and alkylamines has been accomplished under palladium/N-heterocyclic carbene (NHC) catalysis. Owing to its electron deficiency, the leaving arenesulfenate anion would be smoothly released from the palladium center to result… read more here.
Keywords: amination aryl; palladium catalyzed; catalyzed amination; amination ... See more keywords
Metalloporphyrin Catalyzed C–H Amination
Sign Up to like & getrecommendations! Published in 2019 at "ACS Catalysis"
DOI: 10.1021/acscatal.9b00009
Abstract: Direct C–H bond functionalization to form C–N bonds via nitrenoid insertion is one of the most effective strategies to construct N-functionalized molecules of importance. In this context, metalloporphyrins have established themselves as effective catalytic systems… read more here.
Keywords: metalloporphyrin; catalyzed amination; amination; metalloporphyrin catalyzed ... See more keywords
Room-Temperature Cu-Catalyzed Amination of Aryl Bromides Enabled by DFT-Guided Ligand Design.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.3c00500
Abstract: Ullmann-type C-N coupling reactions represent an important alternative to well-established Pd-catalyzed approaches due to the differing reactivity and the lower cost of Cu. While the design of anionic Cu ligands, particularly those by Ma, has… read more here.
Keywords: aryl; catalyzed amination; design; amination aryl ... See more keywords
Nickel-Catalyzed Amination of α-Aryl Methyl Ethers
Sign Up to like & getrecommendations! Published in 2019 at "Synlett"
DOI: 10.1055/s-0039-1690718
Abstract: α-Aryl amines are prevalent in pharmaceutically active compounds and natural products. Herein, we describe a Ni-catalyzed protocol for their synthesis from readily available α-aryl ethers. While α-aryl ethers have been used as electrophiles in Ni-catalyzed… read more here.
Keywords: aryl methyl; methyl ethers; catalyzed amination; amination aryl ... See more keywords