Asymmetric Palladium-Catalyzed Aminochlorination of Unactivated Alkenes.
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DOI: 10.1021/acs.orglett.3c00771
Abstract: A novel Pd-catalyzed enantioselective aminochlorination of alkenes via a 6-endo cyclization is reported herein, which provides easy access to a wide array of structurally diverse 3-chloropiperidines in good yields with excellent enantioselectivities. Notably, both an… read more here.
Keywords: aminochlorination unactivated; palladium catalyzed; asymmetric palladium; aminochlorination ... See more keywords