N-Heterocyclic carbene catalyzed aza-benzoin reaction for access to α-aminoketone molecules containing benzothiazole fragments
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron"
DOI: 10.1016/j.tet.2021.132311
Abstract: Abstract An N-Heterocyclic carbene (NHC) catalyzed aza-benzoin reaction of benzothiazole-2-carboxaldehydes and N-sulfonylimines is reported for the first time. The target benzothiazole-containing aminoketone products bearing different substituents and substitution patterns can be obtained in good to… read more here.
Keywords: aza benzoin; benzothiazole; catalyzed aza; benzoin reaction ... See more keywords
Sliver-Catalyzed 1,3-Aza-Benzyl Migration of Allyl Alcohol.
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DOI: 10.1021/acs.orglett.2c02809
Abstract: Carbon migration of alkenyl alcohols has been recognized as an increasingly viable methodology in organic synthesis. Herein, we disclose a silver-catalyzed 1,3-aza-benzyl migration of allyl alcohols by utilizing chelation-assisted selective cleavage of an unstrained C(sp3)-C(sp3)… read more here.
Keywords: benzyl migration; sliver catalyzed; catalyzed aza; migration ... See more keywords
Sc(OTf)3-Catalyzed Aza-Friedel–Crafts Reaction of Electron-Rich Arenes with Isatin-Derived Ketimines: Access to 3-Amino-3-Aryl-2-Oxindoles
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DOI: 10.1055/s-0036-1588432
Abstract: A Sc(OTf)3-catalyzed aza-Friedel–Crafts reaction of electron-rich arenes with isatin-derived ketimines is disclosed, providing biologically interesting 3-amino-3-aryl-2-oxindoles in moderate to good yields with broad substrate scope. This reaction can be easily scaled up, and the Boc… read more here.
Keywords: otf catalyzed; catalyzed aza; aza friedel; crafts reaction ... See more keywords